The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
The imprint of star formation on stellar pulsations. [PDF]
Nat Commun, 2022 Steindl T, Zwintz K, Vorobyov E.
europepmc +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
An early transition to magnetic supercriticality in star formation. [PDF]
Nature, 2022 Ching TC +7 more
europepmc +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Paradoxical Exudative Retinopathy and Macular Star Formation After Treatment Initiation in Coats Disease. [PDF]
J Vitreoretin Dis, 2022 Kalavar M +3 more
europepmc +1 more source
A universal route for the formation of massive star clusters in giant molecular clouds [PDF]
, 2018 Corey S. Howard +2 more
openalex +1 more source
Fragmentation of the High-mass “Starless” Core G10.21-0.31: A Coherent Evolutionary Picture for Star Formation [PDF]
, 2023 Wenyu Jiao +5 more
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Revealing Multiple Nested Molecular Outflows with Rotating Signatures in HH270mms1-A with ALMA
The Astrophysical JournalWe present molecular line observations of the protostellar outflow associated with HH270mms1 in the Orion B molecular cloud with ALMA. The ^12 CO ( J = 3−2) emissions show that the outflow velocity structure consists of four distinct components of low ...
Mitsuki Omura +2 more
doaj +1 more source