Results 131 to 140 of about 563,924 (339)

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Near Infrared Polarimetry of Dark Clouds and Star Forming Regions - Two Micron Polarization Survey of T Tauri Stars [PDF]

, 1990
Motohide Tamura, S. Sato
openalex   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Ultracool dwarfs in open clusters and star-forming regions

EPJ Web of Conferences, 2013
In this contribution I review the results of the UKIRT Infrared Deep Sky Survey (UKIDSS) Galactic Clusters Survey (GCS) on the Initial Mass Function (IMF) and the current searches for young T dwarfs in open clusters and star-forming regions.
Lodieu Nicolas
doaj   +1 more source

SiO in Star Forming Regions: Barnard 1 and Orion KL [PDF]

, 1994
Satoshi Yamamoto, Hitomi Mikami, Shuji Saito   +2 more
openalex   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

A New Method for Determining the Dust Temperature Distribution in Star‐forming Regions [PDF]

, 1999
Di Li, P. F. Goldsmith, Taoling Xie
openalex   +1 more source

The IRAS 08589-4714 star-forming region

, 2016
Fil: Saldaño, Hugo Pablo. Universidad Nacional de Cordoba. Observatorio Astronomico de Cordoba; Argentina.
Saldaño, H. P., Vásquez, J., Gómez, M., Cappa, C. E., Duronea, N., Rubio López, Mónica   +5 more
openaire   +4 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

B-fields and Dust in Interstellar Filaments Using Dust Polarization (BALLAD-POL). II. Testing the Radiative Torque Paradigm in Musca and OMC-1

The Astrophysical Journal
Polarization of starlight and thermal dust emission caused by aligned dust grains is a valuable tool to characterize magnetic fields ( B -fields) and constrain dust properties. However, the grain alignment physics is not fully understood.
Nguyen Bich Ngoc, Thiem Hoang, Pham Ngoc Diep, Le Ngoc Tram   +3 more
doaj   +1 more source