Results 81 to 90 of about 332,346 (345)

Chemical Processes in Star Forming Regions [PDF]

, 2008
This paper will review the basic concepts of gas-phase and grain surface chemistry of dense molecular clouds, where low mass and high mass stars form. The chemistry of cold pre-stellar cloud cores, where molecular freeze-out and deuterium fractionation dominate, will be presented.
openaire   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

High- and Low-Mass Star Forming Regions from Hierarchical Gravitational Fragmentation. High local Star Formation Rates with Low Global Efficiencies

, 2009
We investigate the properties of "star forming regions" in a previously published numerical simulation of molecular cloud formation out of compressive motions in the warm neutral atomic interstellar medium, neglecting magnetic fields and stellar feedback.
A.-Katharina Jappsen, Ballesteros-Paredes, Ballesteros-Paredes, Ballesteros-Paredes, Ballesteros-Paredes, Beuther, Bigiel, Brunt, Burkert, Caselli, Elmegreen, Elmegreen, Elmegreen, Enrique Vázquez-Semadeni, Evans, Federrath, Federrath, Frisch, Galván-Madrid, Gilberto C. Gómez, Hartmann, Hartmann, Heitsch, Heitsch, Heitsch, Heitsch, Hennebelle, Heyer, Hillenbrand, Ikeda, Javier Ballesteros-Paredes, Jijina, Kirk, Klessen, Klessen, Klessen, Klessen, Klessen, Koyama, Krumholz, Krumholz, Krumholz, Kurtz, Larson, Lee, Li, Matzner, McKee, McKee, Ostriker, Palla, Ralf S. Klessen, Rosas-Guevara, Sandstrom, Tobin, Vázquez-Semadeni, Vázquez-Semadeni, Vázquez-Semadeni, Vázquez-Semadeni, Vázquez-Semadeni, Vázquez-Semadeni, Whitworth   +61 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Structure and Dynamics of the Young Massive Star Cluster Westerlund 1

The Astrophysical Journal
We present a structural and dynamical analysis of the young massive star cluster Westerlund 1 (Wd1). Using multiepoch Hubble Space Telescope observations, we measure the proper motions of 10,346 stars and present an unprecedented determination of cluster
Lingfeng Wei, Peter C. Boyle, Jessica R. Lu, Matthew W. Hosek Jr., Quinn M. Konopacky, Richard G. Spencer, Dongwon Kim, Nicholas Z. Rui, Max Service, D. B. Huang, Jay Anderson   +10 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Origin of optically passive spiral galaxies with dusty star-forming regions: Outside-in truncation of star formation?

, 2010
Recent observations have revealed that red, optically--passive spiral galaxies with little or no optical emission lines, harbour significant amounts of dust-obscured star formation.
Abadi, Bekki, Bekki, Bekki, Bekki, Bekki, Couch, Couch, Dressler, Dwek, Evans, Friel, Gallazzi, Goto, Kenji Bekki, Koopmann, Kronberger, Masters, Meurer, Moran, Navarro, Noguchi, Poggianti, Schmidt, Shioya, Shioya, Spitzer, Sugimoto, Warrick J. Couch, Wilman, Wolf, Wolf, Yamauchi   +32 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Global and Local Infall in the ASHES Sample (GLASHES). I. Pilot Study in G337.541

The Astrophysical Journal
Recent high-angular-resolution observations indicate the need for core growth to form high-mass stars. To understand the gas dynamics at the core scale in the very early evolutionary stages before being severely affected by feedback, we have conducted ...
Kaho Morii, Patricio Sanhueza, Timea Csengeri, Fumitaka Nakamura, Sylvain Bontemps, Guido Garay, Qizhou Zhang   +6 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source