Results 61 to 70 of about 560,529 (289)

Optical Alignment of the Global Precipitation Measurement (GPM) Star Trackers [PDF]

open access: yes, 2013
The optical alignment of the star trackers on the Global Precipitation Measurement (GPM) core spacecraft at NASA Goddard Space Flight Center (GSFC) was challenging due to the layout and structural design of the GPM Lower Bus Structure (LBS) in which the ...
Mclean, Kyle   +5 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A Heavy Flavor Tracker for STAR [PDF]

open access: yes, 2008
The STAR Collaboration proposes to construct a state-of-the-art microvertex detector,the Heavy Flavor Tracker (HFT), utilizing active pixel sensors and silicon strip technology. The HFT will significantly extend the physics reach of the STAR experiment for precision measurement of the yields and spectra of particles containing heavy quarks.
Chasman, C.   +54 more
openaire   +4 more sources

SPACE DEBRIS, ANOTHER ENVIRONMENTAL ISSUE [PDF]

open access: yesChallenges of the Knowledge Society, 2022
Space debris is defunct artificial objects in space which no longer serve a useful function (nonfunctional spacecraft and abandoned launch vehicle stages, mission-related debris, and particularly numerous in Earth orbit, fragmentation debris from the ...
Ioana PĂDURARIU
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Grayscale Iterative Star Spot Extraction Algorithm Based on Image Entropy

open access: yesApplied Sciences
Star trackers are susceptible to interference from stray light, such as sunlight, moonlight, and Earth atmosphere light, in the space environment, resulting in an overall improvement in the star image grayscale, poor background uniformity, low star ...
Qing Zhao   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Resident Space Object (RSO) Tracking in Space-Based, Low Resolution, Non-Constant-Attitude Imagery

open access: yesRemote Sensing
Resident Space Objects (RSOs) are a collection of both man-made and natural objects in near-Earth space. Given their large orbital velocities and rapidly increasing quantity, they pose a collision threat to space assets, necessitating better Space ...
Perushan Kunalakantha   +6 more
doaj   +1 more source

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