Results 51 to 60 of about 4,861,089 (141)
ABSTRACT Introduction People living with visual impairment (VI), defined as a reduction in visual acuity or visual field that cannot be corrected by spectacles or contact lenses, experience health inequalities and are at increased risk of medication‐related safety incidents.
Isabel Adeyemi +9 more
wiley +1 more source
Stargardt’s: Trends in Treatment Modalities [PDF]
Background: This review is aimed at furthering understanding of Stargardt’s, including disease pathophysiology, treatment methods, and the future of vision restoration.
Myers, Dallas
core +1 more source
ABSTRACT Retinal astrocytichamartoma (RAH) is a rare benign glial neoplasm most commonly associated with tuberous sclerosis complex (TSC). Sporadic cases, occurring in the absence of systemic phakomatosis, are uncommon and may closely mimic retinoblastoma, particularly when presenting with a calcified intraocular mass, creating a diagnostic challenge ...
Mesfin Wubishet Gurmu +7 more
wiley +1 more source
ABSTRACT Purpose To characterize the severity‐dependent pattern of accommodative and binocular visual alterations in spectacle‐corrected children with myopic anisometropia, normal best‐corrected visual acuity (BCVA), and no clinically significant binocular vision‐related symptoms.
Ningxin Dou +6 more
wiley +1 more source
Mesopic microperimetry in Stargardt disease: Application and reliability
Abstract Purpose Mesopic microperimetry (mMP) is a promising functional endpoint in clinical trials for Stargardt disease type 1 (STGD1). This study evaluated the test–retest variability of mMP and influencing factors, which is essential for ensuring reliability in future STGD1 trials.
Sybren H. Kootstra +12 more
wiley +1 more source
Abstract Purpose Inherited retinal diseases (IRDs) are a clinically and genetically heterogeneous group of disorders, with ~30% of cases remaining genetically unsolved. Complete congenital stationary night blindness (cCSNB) is a subtype of IRD, usually associated with reduced visual acuity, nystagmus and high myopia.
Filip Spanic +10 more
wiley +1 more source
Background The Retinal Pigmented Epithelium (RPE) is juxtaposed with the photoreceptor outer segments of the eye. The proximity of the photoreceptor cells is a prerequisite for their survival, as they depend on the RPE to remove the outer segments and ...
Griffiths T Daniel +2 more
doaj +1 more source
This study reports the documented case of ABCA4‐associated early‐onset severe retinal dystrophy in China, broadens the mutational spectrum of ABCA4 in this population, and highlights distinct genotype–phenotype correlations that may inform clinical management and genetic counseling.
Nian Li +6 more
wiley +1 more source
Unveiling the Power of Deuterium in Drug Discovery: A Comprehensive Overview
The role of deuterium replacement in drug discovery, its progress, opportunities, and challenges. ABSTRACT Deuterium, the heavy isotope of hydrogen, has unfolded as a cornerstone in modern drug discovery due to its potential to influence metabolic stability and pharmacokinetic behavior.
Mukta Lele +7 more
wiley +1 more source
Low Vision Rehabilitation in Patients with Hereditary Retinal Dystrophy
Objectives: To examine the methods of low vision rehabilitation in patients with hereditary retinal dystrophy. Materials and Methods: This study was conducted in Ankara University Faculty of Medicine, Ophthalmology Department of Low Vision ...
İkbal Seza Petriçli +3 more
doaj +1 more source

