Results 41 to 50 of about 66,607 (349)

Relationships between the acoustic startle response and prepulse inhibition in C57BL/6J mice: a large-scale meta-analytic study

Molecular Brain, 2018
Prepulse inhibition (PPI) is the suppression of a startle reflex response to a startle stimulus that occurs when a weak prepulse stimulus precedes the startle stimulus.
Hirotaka Shoji, Tsuyoshi Miyakawa
semanticscholar   +1 more source

A forward genetic screen identifies Dolk as a regulator of startle magnitude through the potassium channel subunit Kv1.1.

PLoS Genetics, 2021
The acoustic startle response is an evolutionarily conserved avoidance behavior. Disruptions in startle behavior, particularly startle magnitude, are a hallmark of several human neurological disorders.
Joy H Meserve, Jessica C Nelson, Kurt C Marsden, Jerry Hsu, Fabio A Echeverry, Roshan A Jain, Marc A Wolman, Alberto E Pereda, Michael Granato   +8 more
doaj   +1 more source

The Role of Cholinergic Midbrain Neurons in Startle and Prepulse Inhibition

Journal of Neuroscience, 2018
One of the two major cholinergic centers of the mammalian brain is located in the midbrain, i.e., the pedunculopontine tegmentum (PPTg) and the adjacent laterodorsal tegmentum.
E. Azzopardi, A. G. Louttit, C. D. de Oliveira, S. Laviolette, S. Schmid   +4 more
semanticscholar   +1 more source

Reduced Prepulse Inhibition as a Biomarker of Schizophrenia

Frontiers in Behavioral Neuroscience, 2016
The startle response is composed by a set of reflex behaviors intended to prepare the organism to face a potentially relevant stimulus. This response can be modulated by several factors as, for example, repeated presentations of the stimulus (startle ...
Luis Gonzalo De La Casa, Auxiliadora Mena, Juan Carlos Ruiz-Salas, Andrea Puentes, Inmaculada Dorado, Miguel Ruiz-Veguilla   +5 more
doaj   +1 more source

Sensorimotor gating of the startle reflex: what we said 25 years ago, what has happened since then, and what comes next

Journal of Psychopharmacology, 2016
Our 1992 paper, ‘The neural substrates of sensorimotor gating of the startle reflex: a review of recent findings and their implications’, reviewed a series of (then) new and preliminary findings from cross-species studies of prepulse inhibition of the ...
N. Swerdlow, D. Braff, M. Geyer
semanticscholar   +1 more source

Psychometric properties of startle and corrugator response in NPU, Affective Picture Viewing, and Resting State tasks

Psychophysiology, 2016
The current study provides a comprehensive evaluation of critical psychometric properties of commonly used psychophysiology laboratory tasks/measures within the NIMH RDoC.
Jesse T Kaye, Daniel E. Bradford, John J. Curtin   +2 more
semanticscholar   +1 more source

Habituation of reflexive and motivated behaviour in mice with deficient BK channel function

Frontiers in Integrative Neuroscience, 2013
Habituation is considered the most basic form of learning. It describes the decrease of a behavioural response to a repeated non-threatening sensory stimulus and therefore provides an important sensory filtering mechanism.
Marei eTyplt, Magdalena eMirkowski, Erin eAzzopardi, Peter eRuth, Peter K.D. Pilz, Susanne eSchmid   +5 more
doaj   +1 more source

Startle Increases the Incidence of Anticipatory Muscle Activations but Does Not Change the Task-Specific Muscle Onset for Patients After Subacute Stroke

Frontiers in Neurology, 2022
Objectives: To demonstrate the task-specificities of anticipatory muscle activations (AMAs) among different forward-reaching tasks and to explore the StartleReact Effect (SE) on AMAs in occurrence proportions, AMA onset latency or amplitude within these ...
Nan Xia, Nan Xia, Chang He, Yang-An Li, Yang-An Li, Minghui Gu, Minghui Gu, Zejian Chen, Zejian Chen, Xiupan Wei, Xiupan Wei, Jiang Xu, Jiang Xu, Xiaolin Huang, Xiaolin Huang   +14 more
doaj   +1 more source

Startle response related genes [PDF]

, 2011
The startle reaction (also known as the startle response, the startle reflex, or the alarm reaction) is the psychological and physiological response to a sudden unexpected stimulus, such as a flash of light, a loud noise (acoustic startle reflex), or a ...
Li, He, Xiaoxia Li, Stanley Smerin, He Li, Li, Xiaoxia, Lei Zhang, Xian-Zhang Hu, Zhang, Lei, David M. Benedek, Smerin, Stanley, Benedek, David M., Robert Ursano, Ursano, Robert, Hu, Xian-Zhang   +13 more
core   +1 more source

Subcellular Dissection of a Simple Neural Circuit: Functional Domains of the Mauthner-Cell During Habituation

Frontiers in Neural Circuits, 2021
Sensorimotor integration is a pivotal feature of the nervous system for ensuring a coordinated motor response to external stimuli. In essence, such neural circuits can optimize behavioral performance based on the saliency of environmental cues.
Dániel Bátora, Áron Zsigmond, István Z. Lőrincz, Gábor Szegvári, Máté Varga, András Málnási-Csizmadia, András Málnási-Csizmadia   +6 more
doaj   +1 more source