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STAT3 and apoptosis challenges in cancer

International Journal of Biological Macromolecules, 2018
Several studies have processed conceivable evidence for the vital role of Signal Transducer and Activator of Transcription 3 (STAT3) in cancer transformation and carcinogenesis. Therefore, one of the important factors in formation of cancer is STAT3 and for design of novel anticancer drugs is a suitable target.
Nazanin, Fathi   +4 more
openaire   +2 more sources

LncRNA STAT3-AS regulates endometrial receptivity via the STAT3 signaling pathway

Theriogenology
Endometrial receptivity is critical for the successful establishment of pregnancy in ruminants. Interferon tau (IFNT) plays a key role in promoting embryo attachment by activating the Janus kinase/signal transducer and activator of transcription pathway, which induces the expression of a series of interferon-stimulated genes (ISGs).
Yanni, Jia   +11 more
openaire   +2 more sources

Revisiting STAT3 signalling in cancer: new and unexpected biological functions

Nature Reviews. Cancer, 2014
Hua Yu   +4 more
semanticscholar   +1 more source

[STAT3 inhibitor].

Gan to kagaku ryoho. Cancer & chemotherapy, 2011
Clinical efficacies of various molecular-targeted drugs have been recently demonstrated. Most of these drugs are kinase inhibitors. A most successful drug Glivec is an inhibitor of Bcr-Abl fusion kinase, derived from a well-known causative chromosome translocation of chronic myeloid leukemia(CML). Although other kinase inhibitors have also proved to be
openaire   +1 more source

IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis

Cancer Cell, 2020
Valentina Scabia   +2 more
exaly  

Stat3

1998
Tak W. Mak   +4 more
openaire   +1 more source

STAT3 and its targeting inhibitors in osteosarcoma

Cell Proliferation, 2021
Shijie Liao   +2 more
exaly  

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