Results 81 to 90 of about 15,527,786 (403)

Nonfatal Injuries And Illnesses Among State And Local Government Workers [PDF]

open access: yes, 2014
The scope of the Survey of Occupational Injuries and Illnesses was expanded with the 2008 survey to cover a more complete section of the U.S. economy: state and local government workers.
Maloney, Shannon M
core   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

DEVELOPMENT OF THE EXPERT SYSTEM FOR HUMAN RESOURCE MANAGEMENT IN THE STATE GOVERNMENT

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2006
These papers explain the basic elements of construetion of expert svstem for human resource management in state government on the organization level of ministry, state government and offices of state government.
Miroslav Baca
doaj  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

The first experience of two-stage treatment of transsphincteric fistulas of rectum by means of fibrin sealant

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of investigation. To improve the short­term and long­term results of transsphincteric rectal fistulas treatment by patented two­stage method that includes elimination of fistulous tract with the subsequent enzyme treatment of the wound channel and ...
S. A. Frolov   +5 more
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Diagnostics and treatment of Clostridium difficile-associated disease: Guidelines of the Russian gastroenterological association

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of publication. To present with clinical guidelines of the Russian gastroenterological association on Clostridium difficile-associated disease management to practical doctors. Summary. Clostridium difficile-associated disease develops at disorders of
V. T. Ivashkin   +11 more
doaj   +1 more source

Optimal control problems with state constraint governed by Navier-Stokes equations [PDF]

open access: yesarXiv, 2010
This work deals with the existence of optimal solution and the maximum principle for optimal control problem governed by Navier-Stokes equations with state constraint in 3-D. Strong results in 2-D also are given.
arxiv  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

STRUGGLE AGAINST ORGANIZED CRIMINALITY AND CORRUPTION AS SAFETY CONDITION FOR NORT-CAUCASIAN FEDERAL DISTRICT

open access: yesМодернизация, инновация, развитие, 2016
In order to address the problem of safety in the North Caucasian region, suppression of underground gangs’ subversive and terroristic activities have been continuously undertaken for quite a long time within the frames of the military force strategy ...
G. V. Startsev
doaj  

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