Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Theoretical Ideas of Local Government and State Government Development
In this article the characteristic of a theoretical component of model of interaction of local government bodies with the central government, and also development of scientific base in the course of history is given.
Nikolay I. Churinov
doaj
Primary school mobile dental program in New South Wales, Australia: protocol for the evaluation of a state government oral health initiative. [PDF]
Balasubramanian M+16 more
europepmc +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
Preventive health resource allocation decision-making processes and the use of economic evidence in an Australian state government-A mixed methods study. [PDF]
Ananthapavan J+4 more
europepmc +1 more source
COÖPERATION OF STATE AND FEDERAL GOVERNMENTS IN REGISTRATION OF BIRTHS AND DEATHS [PDF]
John Emerson Monger
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Mortality versus Municipal and State Government Spending in American Cities. [PDF]
MacKenzie T, Lebeaux R.
europepmc +1 more source
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul+11 more
wiley +1 more source
References to Evidence-based Program Registry (EBPR) websites for behavioral health in U.S. state government statutes and regulations. [PDF]
Lee MJ+3 more
europepmc +1 more source