Results 81 to 90 of about 3,090,729 (363)
Abstract It is common to suggest that certain threats generate emergency conditions that permit leaders to abjure deontic principles or to violate rights in the name of the common good. The idea that emergencies represent a kind of moral free-for-all has led some to argue that we should reject the concept in its entirety.
openaire +1 more source
Law’s disappearance: the state of exception and the destruction of experience [PDF]
This paper explores the philosophical, political and memorial consequences of the contemporary status of law present in the work of Giorgio Agamben with specific reference to the field of legal history.
Cercel, Cosmin Sebastian
core
Hierarchical confirmatory factor analysis of the flow state scale in exercise [PDF]
In this study, we examined the factor structure and internal consistency of the Flow State Scale using responses of exercise participants.This self-report questionnaire consists of nine subscales designed to assess flow in sport and physical activity. It
Karageorghis, CI +2 more
core +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Estado de excepción neoliberal y resistencia en el sureste de México
In November 2021, the President of Mexico (2018-2024) declared that the priority megaprojects of the National Development Plan (Maya Train, Isthmus of Tehuantepec Interoceanic Corridor, Dos Bocas Refinery) fall within the realm of national security ...
Agustín R. Vázquez García +1 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Factors Regulating the Discharge Frequency in Optomotor Fibres Of Carcinus Maenas [PDF]
The influence of the excited state of the animal on various motor neurone discharges and accompanying muscle action potentials was studied in the eyestalk of the crab, Carcinus maenas.
Fiore, L., Wiersma, C. A. G.
core
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source

