Results 81 to 90 of about 3,021,739 (277)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Colonial sovereignty, forms of life and liminal beings in South Africa [PDF]

open access: yes, 2012
Book synopsis: Svirsky and Bignall assemble leading figures to explore the rich philosophical linkages and the political concerns shared by Agamben and postcolonial theory.
Motha, Stewart
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Racial quotas in university vis-à-vis the state of exception

open access: yesRevista Latinoamericana de Bioética, 2016
There is a close interconnection between Education and Bioethics, as explicitly stated by the Universal Declaration of Bioethics and Human Rights and by the Universal Declaration of Human Rights.
Dario Palhares   +2 more
doaj   +1 more source

The euro and inflation uncertainty in the European Monetary Union [PDF]

open access: yes, 2006
In this paper, we investigate empirically the relationship between inflation and inflation uncertainty in twelve EMU countries. We estimate a time-varying parameter model with a GARCH specification for the conditional volatility of inflation in order to ...
Caporale, GM, Kontonikas, A
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

The threshold of democracy in José Saramago’s 'Seeing'

open access: yesGragoatá, 2018
Seeing was written by José Saramago in 2004, and starts from the assumption that the population can start a silent backlash by casting blank votes in local elections, thus disrupting the normality of the democratic system. Between culpability and action,
Lígia Bernardino
doaj   +1 more source

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