Results 91 to 100 of about 3,634 (300)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Behavior of high performance artificial lightweight aggregate concrete reinforced with hybrid fibers
MATEC Web of Conferences, 2018 In this investigation, sustainable High Performance Lightweight Aggregate Concrete (HPLWAC) containing artificial aggregate as coarse lightweight aggregate (LWA) and reinforced with mono fiber, double and triple hybrid fibers in different types and ...
Khalil Wasan +2 more
doaj +1 more source
Adhesive wood joints under quasi-static and cyclic fatigue fracture Mode II loads
, 2019 This paper investigates the energy release rate (ERR) in Mode II in-plane shear during delamination propagation under quasi-static and cyclic fatigue fracture loading with the 4-point end notched flexure (4-ENF) fracture test specimen. Wood joints bonded
Clerc, Gaspard +5 more
core +1 more source
Modelling shear-flexure interaction in equivalent frame models of slender reinforced concrete walls [PDF]
, 2014 Quasi-static cyclic tests on reinforced concrete (RC) walls have shown that shear deformations can constitute a significant ratio of the total deformations when the wall is loaded beyond the elastic regime.
P. E. Mergos +5 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
MEMS-based conjugate surfaces flexure hinge
, 2015 This paper presents a new concept flexure hinge for MEMS applications and reveals how to design, construct, and experimentally test. This hinge combines a curved beam, as a flexible element, and a pair of conjugate surfaces, whose contact depends on load
VEROTTI, Matteo +3 more
core +2 more sources
Fabrication of green anti-microbial and anti-static cement building bricks
Scientific ReportsThe design cement mix of grade 350 was created in accordance with Egyptian Standards by partially substituting the fine aggregate with WPVC waste in various weight percentages (10, 20, 30, 40, 50, 75, and 100%). A control mix with 0% replacement was also
Abeer Reffaee +3 more
doaj +1 more source
Fibers, 2019 This study presents an experimental investigation of the flexure behavior of exterior beam-column joints made from hybrid concrete (normal concrete (NC) and reactive powder concrete (RPC)) or hybrid reinforcement (steel and carbon fiber reinforced ...
Ammar Yaser Ali +1 more
doaj +1 more source
The effect of voids on the flexural fatigue properties of carbon/epoxy composites
, 2010 The role of voids in composite failures has not been well understood or been characterized. This study presents the result of an investigation aimed at examining the mechanical behaviour of unidirectional carbon fibre-reinforced polymer matrix materials ...
Suhot, Mohamed Azlan
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source