Results 101 to 110 of about 3,634 (300)
Fatigue of Aircraft Structures, 2018 Damage tolerance of composite aircraft structure is one of the main areas of research, important when a new product is being developed. There are a number of variables, such as damage characteristics (dent depth, delamination area) and loading parameters
Zalewska Małgorzata
doaj +1 more source
Preliminary characterization of anelastic effects in the flexure mechanism for a new Kibble balance at NIST [PDF]
A new Kibble balance is being built at the National Institute of Standards and Technology (NIST). For the first time in one of the highly accurate versions of this type of balance, a single passive flexure mechanism is used for both modes of operation ...
Seifert, Frank +4 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Effects of moisture on torsion and flexure properties of graphite-epoxy composites
, 1979 The effects of moisture and temperature on unidirectional and multi-ply laminates of T300/934 and AS/3501 graphite-epoxy systems were investigated.
Sumsion, H. T., Adamson, M. J.
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, 2017 This paper deals with four-point flexure tests on hybrid P-joints, made out of multi-layer carbon fiber/epoxy resin reinforced composites, processed using the RTM (resin transfer moulding) technique.
Bai, J.B. +3 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Flexural Performance of Alkali-Activated Slag Cements under Quasi-Static and Impact Loading
Journal of Materials in Civil Engineering, 2017 AbstractEffects of silicate modulus (Ms) of an activator solution and the matrix components of alkali-activated slag cement (AASC) on the flexural parameters of AASC mortars were investigated under static and low-velocity impact loadings. AASC mixtures in two different Ms (SiO2/Na2O) ratios were prepared by the partial replacement of ground granulated ...
Yardimci, Mert Yucel +2 more
openaire +4 more sources
Modified hyperbolic shear deformation theory for static flexure analysis of thick isotropic beam
, 2017 A hyperbolic shear deformation theory for thick isotropic beams is developed where the displacements are defined using a meaningful function which is more physical and directly comparable with other higher order theories.
Jasotharan, S, Weerasekera, IRA
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