Results 71 to 80 of about 1,066,098 (345)

3D printed meta-sandwich structures: Failure mechanism, energy absorption and multi-hit capability

Materials & Design, 2018
A new class of lightweight and 3D printable architected sandwich structures, named as meta-sandwich structures, has been introduced. These lightweight sandwich structures, which have been made of mechanical metamaterials as the core, show many advantages
H. Yazdani Sarvestani, A.H. Akbarzadeh, A. Mirbolghasemi, K. Hermenean   +3 more
doaj   +1 more source

Design and control methodology of a 3-DOF flexure-based mechanism for micro/nano-positioning [PDF]

, 2015
A 3-DOF (X–Y–θZ) planar flexure-based mechanism is designed and monolithically manufactured using Wire Electro-Discharge Machining (WEDM) technology. The compact flexure-based mechanism is directly driven by three piezoelectric actuators (PZTs) through ...
Guo, Z., Liu, C., Liu, Xianping, Shirinzadeh, B., Tian, Yanling, Wang, F., Zhang, D.   +6 more
core   +1 more source

Improving Support Stiffness of Flexure Mechanisms by Statically Balancing

, 2021
Static balance eliminates the actuation stiffness of flexure mechanisms and thereby reduces the motor effort and unwanted heat production. However, this typically comes at the cost of lowered support stiffness and stroke. This paper aims to show that the maximum stresses in the flexures may be reduced as well by static balance.
de Jong, Jan, Theans, Sebastiaan, Epping, Lars, Brouwer, Dannis Michel   +3 more
openaire   +1 more source

Variational analysis of gradient elastic flexural plates under static loading

International Journal of Solids and Structures, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Papargyri-Beskou, S., Giannakopoulos, A.E., Beskos, D.E.   +2 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Influence of seismic loading on axial load variation in reinforced concrete columns [PDF]

e-GFOS, 2018
Experimental tests demonstrated the importance of the axial load variation in the seismic response of RC columns, namely, through the reduction in the strength capacity, reduced deformation capacity, and reduced energy dissipation capacity.
Hugo Rodrigues, André Furtado, António Arêde, Humberto Varum   +3 more
doaj   +1 more source

Modelling dispersion effects in paper-effective thickness estimates [PDF]

, 1994
The structural properties of paper and cardboard are important for the design of containers and of packaging. Amcor, a Melbourne-based producer of packaging, pulp and paper products, proposed the initial problem of explaining the large discrepancies ...
Rose, F.
core  

Statics Analysis and Optimization Design for a Fixed-Guided Beam Flexure

Journal of Advanced Engineering and Computation, 2020
The ratchet mechanism has been used to ensure moving in one direction of rotation, i.e. either clockwise or counterclockwise. This mechanism is designed based on fixed-guided beam flexures to reduce friction and improves accuracy compared to the traditional mechanism. This paper presents a static analysis and parameter optimization for the fixed-guided
Ngoc Thoai Tran, Thanh-Phong Dao
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source