Results 51 to 60 of about 7,950 (309)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Energies, 2022 Reliability and safety must be carefully considered in today’s power systems, which are rapidly evolving toward ever higher penetration of renewable, inverter-based generation units.
Giuseppe Marco Tina +2 more
doaj +1 more source
Sensor & instrumentation system : series 2 [PDF]
, 2017 This book is an introduction to a number of the topics in sensor and instrumentation systems. Many of the topics describe the design experiments and system measurement especially in sensor applications.
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Smart control application in the oscillations using FACTS (STATCOM and SVC)
Tecnura, 2017 Context: Reducing the oscillations of the electrical power systems is an important task in order to maintain their stability. This paper presents a methodology for adjusting the parameters of a fuzzy oscillations controller with a Static Var Compensator (
Alfonso James Alzate Gomez +2 more
doaj +1 more source
On the Application of heuristic Method and Saddle Node Bifurcation for Optimal Placement of FACTS Devices in Power System [PDF]
, 2011 This study focuses on an optimal placement of five major types of FACTS devices, namely, Static Var Compensator (SVC), Thyristor Controlled Series Compensator (TCSC), Static Synchronous Compensator (STATCOM), Static Synchronous Series Compensator (SSSC ...
Ab Kadir, Mohd Zainal Abidin +2 more
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A practical dynamic phasor model of static VAR compensator [PDF]
, 2014 Author name used in this publication: Ka Wing ChanRefereed conference paper2006-2007 > Academic research: refereed > Refereed conference paperVersion of ...
Chan, KWK, E, Z, Fang, D
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Optimal sizing of static VAR compensator using bees algorithm for cost minimization [PDF]
, 2020 This paper presents the application of Bees Algorithm (BA) technique to find the optimal sizing of Static Var Compensator (SVC) to achieve the power system economic generation and dispatch.
Azman, Zulkifli +7 more
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