Results 61 to 70 of about 7,950 (309)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Application Research of Static Var Generator in Wind Power System

Gong-kuang zidonghua, 2012
The paper analyzed and compared dynamic response time and harmonic characteristics of thyristor controlled reactor type static var compensator and static var generator, and got a conclusion that static var generator has quicker dynamic response speed and
WANG Gang, ZHAO Li-jun, LI Jie, YU Ya-bing   +3 more
doaj  

Voltage Stability Analysis of Grid-Connected Wind Farms with FACTS: Static and Dynamic Analysis [PDF]

, 2015
Recently, analysis of some major blackouts and failures of power system shows that voltage instability problem has been one of the main reasons of these disturbances and networks collapse.
Angeles-Camacho C., Ayodele T. R., Bansal R., Camm E. H., Cañizares C., Fu R., Hingorani N. G., Kundur P., Rozlan M., Saeed A. M.   +9 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Enhancement of voltage profile by incorporation of SVC in power system networks by using optimal load flow method in MATLAB/Simulink environments

Energy Reports, 2018
Flexible AC Transmission Systems (FACTS) controllers could be a suitable alternative to provide reactive power support at the load centers locally and hence keep the voltages within their safe operating limits.
Bindeshwar Singh, Garima Agrawal
doaj   +1 more source

Устойчивость электропередачи, оборудованной статическим тиристорным компенсатором реактивной мощности [PDF]

, 2016
Объектом исследования является устойчивость электропередачи, оборудованной статическим тиристорным компенсатором реактивной мощности. Цель работы – исследование принципа работы статического тиристорного компенсатора и оценка его влияния на параметры сети,
Петров, Артём Сергеевич
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Minimization of Active Transmission Loss in Power Systems using Static Var Compensator [PDF]

, 2018
Increasing demand for electrical power as a result of modern civilization has imposed challenges such as voltage instability, transmission loss, and power factor fluctuations on power systems. In an attempt to overcome these challenges, FACTS devices are
Adejumobi, I. A., Amuta, Elizabeth, Matthew, Simeon, Wara, S.T.   +3 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Measurement-Based Analysis of Static Var Compensator Effects in Industrial Rolling Mill Grids

Energies
Power quality is a continuous concern in industry, especially in steel mills operating with nonlinear, fluctuating, and unbalanced loads. This paper investigates the influence of a Static Var Compensator (SVC) on power quality parameters in a hot ...
Petru Ivascanu, Manuela Panoiu, Caius Panoiu   +2 more
doaj   +1 more source