Results 111 to 120 of about 124,347 (217)

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

TRIM31–LOX‐1 Axis: A Novel Therapeutic Frontier in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis, driven by a vicious cycle of lipid accumulation and chronic inflammation, underlies most cardiovascular diseases. Macrophages exacerbate this process by internalizing oxidized low‐density lipoprotein (oxLDL), forming foam cells, and releasing inflammatory mediators. A recent study published in Circulation identified the TRIM31–
Qian Zhang, Cheng Xue Qin
wiley   +1 more source

Prime time for the use of statins in MPNs: from comorbidity drugs to disease-modifying partners. [PDF]

Blood Adv
Hasselbalch HC.
europepmc   +1 more source

Metrnl: A Novel Therapeutic Target in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Severity of periodontitis and risk of ischemic stroke: A systematic review and meta‐analysis

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a prevalent chronic inflammatory disease with a systemic inflammatory burden and is implicated with vascular pathology. This systematic review and meta‐analysis evaluates the association between varying severities of periodontitis and ischemic stroke with various diagnostic criteria.
Steven Sitt, Chloe J. Chang, Chin‐Wei Wang   +2 more
wiley   +1 more source

Modulation of Orthodontic Tooth Movement by Statins: A Systematic Review of Animal Studies. [PDF]

Dent J (Basel)
Crispino R, Zara F, Vella M, Colaianni L, Maspero C, Serafin M, Caprioglio A.   +6 more
europepmc   +1 more source

Association Between Preoperative Dyslipidemia and the Prognosis of Patients With Endometrial Cancer: A Retrospective Cohort Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Endometrial cancer (EC) is closely related to metabolic disorders. We aimed to investigate whether preoperative dyslipidemia independently affects the prognosis of patients with EC. One hundred and ninety‐four women diagnosed with EC by pathology and who had undergone standardized surgical treatment at the Affiliated Hospital of Jining Medical
Song Li, Rong‐He Sun, Qing Chen, Zeng‐Shu Huang, Yun‐Fei Wang, Chang‐Zhong Li   +5 more
wiley   +1 more source

Targeting the mevalonate pathway with statins overcomes acquired resistance to KRAS^G12C inhibitors in non-small cell lung cancer. [PDF]

Exp Hematol Oncol
Lin W, Chen QA, Yang Y, Gao Y, He J.
europepmc   +1 more source

Joint and Independent Associations of Dietary Antioxidant Intakes With Advanced Stages in Older Patients With Cardiovascular‐Kidney‐Metabolic Syndrome

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study explored the association between the composite dietary antioxidant index (CDAI) and cardiovascular‐kidney‐metabolic (CKM) progression in an older population. Using data from NHANES 2001–2020, we analyzed 4974 adults aged ≥ 60 years with CKM syndrome. The CDAI was calculated from the intake of six dietary antioxidants.
Fu‐Shan Qiu, Jian‐Chao Qi, Mei‐Zhu Lin, Jun‐Hua Ke   +3 more
wiley   +1 more source

Olfactory Dysfunction and Metabolic Syndrome Components: A Systematic Review and Meta‐Analysis

The Laryngoscope, EarlyView.
ABSTRACT Objective To elucidate the association between olfactory dysfunction (OD) and metabolic syndrome components. Data Sources PubMed (National Library of Medicine—National Institutes of Health), Scopus (Elsevier), CINAHL Complete (EBSCOhost), and the Cochrane Library (Wiley) databases were searched from inception through March 23rd, 2026.
Neeti Gandra, Kaitlyn A. Roberts, Shaun A. Nguyen, Pete Peters, Lauren A. Howser, Zachary M. Soler, Rodney J. Schlosser   +6 more
wiley   +1 more source