Results 281 to 290 of about 150,085 (313)
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Expert Opinion on Investigational Drugs, 2001
The beneficial effect of beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) in primary prevention of coronary artery disease in those with hypercholesterolaemia and in secondary prevention in those with established coronary vascular disease are now well known.
N, Delanty, C J, Vaughan, N, Sheehy
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The beneficial effect of beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) in primary prevention of coronary artery disease in those with hypercholesterolaemia and in secondary prevention in those with established coronary vascular disease are now well known.
N, Delanty, C J, Vaughan, N, Sheehy
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Seminars in Vascular Medicine, 2004
Lipid abnormalities play an important part in raising the cardiovascular risk in diabetic subjects. The main components of diabetic dyslipidemia are increased plasma triglycerides, low concentration of high-density lipoprotein cholesterol, preponderance of small, dense low-density lipoprotein, and excessive postprandial lipemia.
Rafael, Carmena, D John, Betteridge
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Lipid abnormalities play an important part in raising the cardiovascular risk in diabetic subjects. The main components of diabetic dyslipidemia are increased plasma triglycerides, low concentration of high-density lipoprotein cholesterol, preponderance of small, dense low-density lipoprotein, and excessive postprandial lipemia.
Rafael, Carmena, D John, Betteridge
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Medicina Clínica (English Edition), 2015
Statins are the most widely used drugs for both primary and secondary prevention of cardiovascular diseases and those associated with atherosclerosis. About 25 million people are on statin therapy in the world. Although they are well tolerated by most patients and have a safety profile, some patients have muscle level alterations.
Marcelo, Alvarado Cárdenas +2 more
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Statins are the most widely used drugs for both primary and secondary prevention of cardiovascular diseases and those associated with atherosclerosis. About 25 million people are on statin therapy in the world. Although they are well tolerated by most patients and have a safety profile, some patients have muscle level alterations.
Marcelo, Alvarado Cárdenas +2 more
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Current Atherosclerosis Reports, 2007
The incidence and prevalence of dementia are increasing. Dementia is a major cause of disability. Alzheimer's disease (AD) is the most common type of dementia. There are no good prevention or treatment options. Experimental animal and laboratory studies have suggested that cholesterol metabolism in the brain is important in the causal pathway for ...
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The incidence and prevalence of dementia are increasing. Dementia is a major cause of disability. Alzheimer's disease (AD) is the most common type of dementia. There are no good prevention or treatment options. Experimental animal and laboratory studies have suggested that cholesterol metabolism in the brain is important in the causal pathway for ...
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Vascular Pharmacology, 2007
Statins have been shown to have pleiotropic effects apart from serum lipid-lowering effect in human. One of the major target organs for the effects of statins is the vascular endothelium, which plays an important role in the development of atherosclerosis and angiogenesis.
Masaaki, Ii, Douglas W, Losordo
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Statins have been shown to have pleiotropic effects apart from serum lipid-lowering effect in human. One of the major target organs for the effects of statins is the vascular endothelium, which plays an important role in the development of atherosclerosis and angiogenesis.
Masaaki, Ii, Douglas W, Losordo
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BMJ, 2014
Lots of lessons, but we still need the data An expert panel convened by The BMJ has concluded that two articles published last year1 2 and corrected in May should not be retracted.3 The panel’s report comes after a lengthy and public row over proposals to extend the use of statins to healthy people at low risk of heart disease.4 What are the lessons ...
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Lots of lessons, but we still need the data An expert panel convened by The BMJ has concluded that two articles published last year1 2 and corrected in May should not be retracted.3 The panel’s report comes after a lengthy and public row over proposals to extend the use of statins to healthy people at low risk of heart disease.4 What are the lessons ...
openaire +2 more sources