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Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper +25 more
wiley +1 more source
Retention of orthodontic aligners with different gingival margin designs on three-dimensionally printed models representing varying degrees of marginal tissue recession. [PDF]
Bortoli NA +4 more
europepmc +1 more source
Impact of Attendance at Flipped Classroom Sessions on Renal Pathophysiology Scores. [PDF]
Angeles DM, Loo LK.
europepmc +1 more source
The Abelian group structure of full factorial designs. [PDF]
Altieri NA.
europepmc +1 more source
A tutorial on conducting sample size and power calculations for detecting treatment effect heterogeneity in cluster randomized trials with linear mixed models. [PDF]
Ryan Baumann M +6 more
europepmc +1 more source
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Statistical Molecular Design of Building Blocks for Combinatorial Chemistry
Journal of Medicinal Chemistry, 2000The reduction of the size of a combinatorial library can be made in two ways, either base the selection on the building blocks (BB's) or base it on the full set of virtually constructed products. In this paper we have investigated the effects of applying statistical designs to BB sets compared to selections based on the final products.
A, Linusson +3 more
openaire +2 more sources

