Results 51 to 60 of about 339,713 (264)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Quaternion Statistical Submanifolds and Submersions

open access: yesMathematics
This paper aims to develop a general theory of quaternion Kahlerian statistical manifolds and to study quaternion CR-statistical submanifolds in such ambient manifolds.
Aliya Naaz Siddiqui, Fatimah Alghamdi
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Properties and Applications of Extended Hypergeometric Functions

open access: yesIngeniería y Ciencia, 2014
In this article, we study several properties of extended Gauss hypergeometric and extended confluent hypergeometric functions. We derive several integrals, inequalities and establish relationship between these and other special functions.
Daya Krishna Nagar   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Impact toughness and dynamic constitutive model of geopolymer concrete after water saturation

open access: yesScientific Reports
The dynamic compression test of geopolymer concrete (GC) before and after water saturation was carried out by the split Hopkinson pressure bar (SHPB). And the effects of water saturation and strain rate on impact toughness of GC were studied.
Tiecheng Yan   +2 more
doaj   +1 more source

Alpha-Power Pareto distribution: Its properties and applications.

open access: yesPLoS ONE, 2019
In Statistical theory, inclusion of an additional parameter to standard distributions is a usual practice. In this study, a new distribution referred to as Alpha-Power Pareto distribution is introduced by including an extra parameter.
Shumaila Ihtisham   +4 more
doaj   +1 more source

Dilemma of t-tests: Retaining or discarding choice and solutions [PDF]

open access: yesComputational Ecology and Software, 2022
The t-test theory has laid the foundation of modern statistics and it is one of the main contents of statistics. This theory can be found in all statistics textbooks and is at the core of almost all applied statistics courses.
WenJun Zhang
doaj  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Experimental Test of the “Special State” Theory of Quantum Measurement

open access: yesEntropy, 2012
An experimental test of the “special state” theory of quantum measurement is proposed. It should be feasible with present-day laboratory equipment and involves a slightly elaborated Stern–Gerlach setup.
Lawrence S. Schulman
doaj   +1 more source

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