Results 61 to 70 of about 5,428,123 (293)

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Statistical Mechanics of Black Holes

, 1992
We analyze the statistical mechanics of a gas of neutral and charged black holes. The microcanonical ensemble is the only possible approach to this system, and the equilibrium configuration is the one for which most of the energy is carried by a single ...
B. Harms, D. Garfinkle, G. 't Hooft, G. W. Gibbons, J. D. Bekenstein, J. Preskill, M. Bowick, R. Hagedorn, Robert D. Carlitz, S. Coleman, S. W. Hawking, S. W. Hawking, Steven Frautschi, W. Thirring, Y. Leblanc   +14 more
core   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita   +8 more
wiley   +1 more source

Stationary nonequilibrium statistical mechanics [PDF]

Encyclopedia of Mathematical Physics, ed. J.P. Francoise, G.L. Naber, Tsou Sheung Tsun, 3, 530--539, 2006, Elsevier, 2005
A brief review on the dynamical systems approach to nonequilibrium statistical mechanics and chaotic ...
arxiv  

Representative Ensembles in Statistical Mechanics

, 2007
The notion of representative statistical ensembles, correctly representing statistical systems, is strictly formulated. This notion allows for a proper description of statistical systems, avoiding inconsistencies in theory.
Bogolubov N. N., Bogolubov N. N., Bogolubov N. N., Bogolubov N. N., Courteille P. W., Gibbs J. W., Kleinert H., Pitaevskii L., ter Haar D., V. I. YUKALOV, Yukalov V. I.   +10 more
core   +1 more source

CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti‐tumoral compounds

Molecular Oncology, EarlyView.
FOXL2 c.402C>G mutation drives granulosa cell tumors. Using CRISPR technology, we selectively corrected this mutation, reducing malignancy and increasing sensitivity to dasatinib and ketoconazole. Transcriptomic changes revealed potential therapeutic targets, demonstrating CRISPR's promise for treating this rare ovarian cancer.
Sandra Amarilla‐Quintana, Paloma Navarro, Iván Hernández, Alejandra Ramos, Ana Montero‐Calle, Pablo Cabezas‐Sainz, Maria J Barrero, Diego Megías, Borja Vilaplana‐Martí, Carolina Epifano, Déborah Gómez‐Dominguez, Sara Monzón, Isabel Cuesta, Laura Sánchez, Rodrigo Barderas, Jesús García‐Donas, Alberto Martín, Ignacio Pérez de Castro   +17 more
wiley   +1 more source

Deriving Landauer's erasure principle from statistical mechanics [PDF]

arXiv, 2005
We present a concise derivation of Landauer's erasure principle from the postulates of statistical mechanics, along with a small number of additional but uncontroversial axioms.
arxiv  

Some Open Points in Nonextensive Statistical Mechanics [PDF]

, 2011
We present and discuss a list of some interesting points that are currently open in nonextensive statistical mechanics. Their analytical, numerical, experimental or observational advancement would naturally be very welcome.
arxiv   +1 more source

Statistical Mechanics of Community Detection

, 2006
Starting from a general \textit{ansatz}, we show how community detection can be interpreted as finding the ground state of an infinite range spin glass. Our approach applies to weighted and directed networks alike.
B. Everitt, B. Kernighan, I. Kanter, Jörg Reichardt, L. Danon, M. Newman, P. Erdős, S. Wasserman, Stefan Bornholdt   +8 more
core   +1 more source

Whole‐genome sequencing of cell‐free DNA reveals DNA of tumor origin in plasma from patients with colorectal adenomas

Molecular Oncology, EarlyView.
Tumor‐informed whole‐genome sequencing (MRD‐EDGESNV) was applied to detect circulating tumor DNA (ctDNA) in patients with colorectal adenomas. Using a 95% specificity threshold, established from stage III colorectal cancer patients, ctDNA was detected in 50% of symptomatic and 25% of asymptomatic adenoma cases with median tumor fractions of 5.9 × 10−5 ...
Amanda Frydendahl, Adam J. Widman, Nadia Øgaard, Anushri Arora, Daniel Halmos, Jesper Nors, Johanne Ahrenfeldt, Tenna V. Henriksen, Christina Demuth, Line Raaby, Mads H. Rasmussen, Christina Therkildsen, Dan A. Landau, Claus L. Andersen   +13 more
wiley   +1 more source