A Systematic Comparison of Various Statistical Alignment Models
International Conference on Computational Logic, 2003 We present and compare various methods for computing word alignments using statistical or heuristic models. We consider the five alignment models presented in Brown, Della Pietra, Della Pietra, and Mercer (1993), the hidden Markov alignment model ...
F. Och, H. Ney
semanticscholar +1 more source
J/Psi suppression in colliding nuclei: statistical model analysis
, 2000 We consider the $J/\Psi$ suppression at a high energy heavy ion collision. An ideal gas of massive hadrons in thermal and chemical equilibrium is formed in the central region. The finite-size gas expands longitudinally in accordance with Bjorken law. The
A. Capella +46 more
core +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Understanding the Nonlinear Response of SiPMs
SensorsA systematic study of the nonlinear response of Silicon Photomultipliers (SiPMs) was conducted through Monte Carlo (MC) simulations. The MC code was validated against experimental data for two different SiPMs.
Víctor Moya-Zamanillo, Jaime Rosado
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Statistical Mechanics of Transcription-Factor Binding Site Discovery Using Hidden Markov Models [PDF]
, 2010 Pankaj Mehta +2 more
openalex +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
AIRCRAFT ROUGH LANDING CRITERIA ARGUMENTATION BASED ON FLIGHT DATA READOUTS FROM MSRP-A-02
Научный вестник МГТУ ГА, 2016 Article considers methods of formation and argumentation of rough landing criteria based on the on-board MSRP-A-02 recorder data with an example of IL-76TD with PS-90A-76 gas-turbine engines.
V. P. Filippov
doaj
Modeling of RO/NF membrane rejections of PhACs and organic compounds: a statistical analysis [PDF]
, 2008 Victor Yangali-Quintanilla +3 more
openalex +1 more source