Results 111 to 120 of about 34,159,249 (310)

Engaging and motivating students with authentic statistical projects in a capstone unit

open access: yes, 2015
Students preparing for professional statistical work can benefit from experience with real statistical problems presented by real clients and requiring them to engage with the complete problem-solving process without the usual cues of ‘textbook’ examples.
Bilgin, Ayse A.   +2 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Analyzing the Risk of Divorce among Divorced Women with Children Using Time-Dependent Cox Model [PDF]

open access: yesTaḥqīqāt-i ̒Ulūm-i Raftārī
Aim and Background: Divorce is one of the harms that has various personal, psychological and social dimensions and severely affects children. Therefore, studies in this field are always of interest to researchers and policymakers in the field of family ...
Mahsa Saadati, Arezoo Bagheri
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Robust Unsupervised Spatial-Kinematic Coupling for Satellite Laser Ranging Signal Extraction

open access: yesRemote Sensing
In satellite and space debris laser ranging, photon-counting time-of-flight sequences exhibit spatio-temporal echo coherence and deterministic orbital constraints. We propose an unsupervised framework exploiting this spatial-kinematic coupling to extract
Yi Chen   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Network degree distribution estimation and its application to the susceptible-infectious-susceptible (SIS) epidemic model

open access: yesApplied Network Science
In this study, we consider the classical susceptible–infectious–susceptible (SIS) model on heterogeneous networks and introduce a mixture of truncated zeta (MTZ) distributions to model degree heterogeneity more flexibly.
Heng-Yun Ku   +2 more
doaj   +1 more source

The Empirical Bayes Estimators of the Variance Parameter of the Normal Distribution with a Normal-Inverse-Gamma Prior Under Stein’s Loss Function

open access: yesAxioms
For the hierarchical normal and normal-inverse-gamma model, we derive the Bayesian estimator of the variance parameter in the normal distribution under Stein’s loss function—a penalty function that treats gross overestimation and underestimation equally ...
Ying-Ying Zhang
doaj   +1 more source

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