Results 91 to 100 of about 2,324,497 (297)

Statistical Inference in Calibrated Models [PDF]

open access: yesJournal of Applied Econometrics, 1994
SUMMARY This paper describes a Monte Carlo procedure to assess the performance of calibrated dynamic general equilibrium models. The procedure formalizes the choice of parameters and the evaluation of the model and provides an efficient way to conduct a sensitivity analysis for perturbations of the parameters within a reasonable range.
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Empirical Bayes Estimators of the Variance Parameter of the Normal Distribution with a Normal-Inverse-Gamma Prior Under Stein’s Loss Function

open access: yesAxioms
For the hierarchical normal and normal-inverse-gamma model, we derive the Bayesian estimator of the variance parameter in the normal distribution under Stein’s loss function—a penalty function that treats gross overestimation and underestimation equally ...
Ying-Ying Zhang
doaj   +1 more source

Integrating between-host transmission and within-host immunity to analyze the impact of varicella vaccination on zoster

open access: yeseLife, 2015
Varicella-zoster virus (VZV) causes chickenpox and reactivation of latent VZV causes herpes zoster (HZ). VZV reactivation is subject to the opposing mechanisms of declining and boosted VZV-specific cellular mediated immunity (CMI).
Benson Ogunjimi   +3 more
doaj   +1 more source

Statistical Modeling of FSO Fronthaul Channel for Drone-based Networks

open access: yes, 2017
We consider a drone-based communication network, where several drones hover above an area and serve as mobile remote radio heads for a large number of mobile users.
Ajam, Hedieh   +5 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Statistical aspects of carbon fiber risk assessment modeling [PDF]

open access: yes
The probabilistic and statistical aspects of the carbon fiber risk assessment modeling of fire accidents involving commercial aircraft are examined. Three major sources of uncertainty in the modeling effort are identified.
Gross, D., Miller, D. R., Soland, R. M.
core   +1 more source

Statistical modeling, parameter estimation and measurement planning for PV degradation [PDF]

open access: yes, 2017
Photovoltaics (PV) degradation is a key consideration during PV performance evaluation. Accurately predicting power delivery over the course of lifetime of PV is vital to manufacturers and system owners.
Lim, Li Hong Idris   +4 more
core  

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