Results 81 to 90 of about 775,359 (318)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Basic Ideas to Approach Metastability in Probabilistic Cellular Automata [PDF]

open access: yes, 2016
Cellular Automata are discrete--time dynamical systems on a spatially extended discrete space which provide paradigmatic examples of nonlinear phenomena.
Mathematical Modeling   +4 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

A Statistical Model for Helices with Applications [PDF]

open access: yesBiometrics, 2018
Summary Motivated by a cutting edge problem related to the shape of -helices in proteins, we formulate a parametric statistical model, which incorporates the cylindrical nature of the helix. Our focus is to detect a “kink,” which is a drastic change in the axial direction of the helix.
Mardia, KV, Sriram, K, Deane, CM
openaire   +5 more sources

Bayesian model with application to a study of dental caries

open access: yesBMC Oral Health, 2019
Background Dental caries are a significant public health problem. It is a disease with multifactorial causes. In Sub-Sahara Africa, Ethiopia is one of the countries with a high record of dental caries.
Mekuanint Simeneh Workie   +1 more
doaj   +1 more source

Sparse Multicategory Generalized Distance Weighted Discrimination in Ultra-High Dimensions

open access: yesEntropy, 2020
Distance weighted discrimination (DWD) is an appealing classification method that is capable of overcoming data piling problems in high-dimensional settings. Especially when various sparsity structures are assumed in these settings, variable selection in
Tong Su   +8 more
doaj   +1 more source

Statistical modeling for degradation data [PDF]

open access: yes, 2017
This book focuses on the statistical aspects of the analysis of degradation data. In recent years, degradation data analysis has come to play an increasingly important role in different disciplines such as reliability, public health sciences, and finance.
Tsai, Tzong-Ru   +3 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Local Statistical Modeling via Cluster-Weighted Approach with Elliptical Distributions [PDF]

open access: yes
Cluster Weighted Modeling (CWM) is a mixture approach regarding the modelisation of the joint probability of data coming from a heterogeneous population.
Giorgio Vittadini   +2 more
core  

Unified Statistical Modeling for Circuit Simulation [PDF]

open access: yes, 2003
Accurate statistical simulation and modeling are important for IC design. Different types of statistical simulation require different types of statistical models. In this paper a unified approach to statistical modeling and characterization is presented.
Patrick G. Drennan, Colin C. Mcandrew
core  

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