Results 141 to 150 of about 2,290,848 (276)

A deep dive into statistical modeling of RNA splicing QTLs reveals variants that explain neurodegenerative disease. [PDF]

Am J Hum Genet
Wang D, Gazzara MR, Jewell S, Wales-McGrath BD, Yang K, Brown CD, Choi PS, Barash Y.   +7 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Stable isotope and multi-elemental analysis combined with statistical modeling for saffron origin authentication. [PDF]

Food Chem X
Terro C, Strojnik L, Potočnik D, Hudobivnik MJ, Mazej D, Bontempo L, Eddabdouby M, Amenzou NE, Moncef B, Kelly S, Ogrinc N.   +10 more
europepmc   +1 more source

Microarchitecture-Independent Cache Modeling for Statistical Simulation [PDF]

, 2006
De Bosschere, Koen, Eeckhout, Lieven, Genbrugge, Davy   +2 more
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Prolonged growth and extended subadult development in the <i>Tyrannosaurus rex</i> species complex revealed by expanded histological sampling and statistical modeling. [PDF]

PeerJ
Woodward HN, Myhrvold NP, Horner JR.
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Statistical modeling the seroprevalence of hepatitis B among the pregnant women attending specialist hospital, Idah, kogi state, Nigeria. [PDF]

BMC Infect Dis
Aye G, Olusegun O.
europepmc   +1 more source

spmodel: Spatial statistical modeling and prediction in R. [PDF]

PLoS One, 2023
Dumelle M, Higham M, Ver Hoef JM.
europepmc   +1 more source

Modeling Human Performance on Statistical Word Segmentation Tasks [PDF]

, 2007
Frank, Michael C., Goldwater, Sharon, Griffiths, Thomas L., Mansinghka, Vikash, Tenenbaum, Joshua B.   +4 more
core