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Experimental optimization of statistical simulation [PDF]

Proceedings of the 7th conference on Winter simulation - WSC '74, 1974
Although simulation involves solving a mathematical model through experimentation, the literature of simulation does not reflect a broad, sustained interest in the design of simulation experiments. The objective of this paper is to fulfill a part of this need by suggesting a general five-phase experimental approach for determining the optimum for a ...
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Effective targeted planning of optoelectronic spacecraft operation

Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение
The article presents an algorithm for optimizing targeted operation of spacecraft by including in the planning algorithm the requirements for distinguishing consumers, clouds and dynamics of changing the priority of survey areas.
R. R. Khalilov
doaj   +1 more source

Statistical Learning For End-To-End Simulations [PDF]

IGARSS 2018 - 2018 IEEE International Geoscience and Remote Sensing Symposium, 2018
Preprint, paper published in IGARSS 2018 - 2018 IEEE International Geoscience and Remote Sensing Symposium, Valencia, 2018, pp.
Jorge Vicent 0001, Jochem Verrelst, Juan Pablo Rivera Caicedo, Neus Sabater, Jordi Muñoz-Marí, Gustau Camps-Valls, José F. Moreno   +6 more
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Perfect posterior simulation for mixture and hidden Markov models [PDF]

, 2010
In this paper we present an application of the read-once coupling from the past algorithm to problems in Bayesian inference for latent statistical models.
Berthelsen, Kasper Klitgaard, Laird A. Breyer, Berthelsen, Kasper K., Kasper K. Berthelsen, Roberts, Gareth O., Breyer, Laird A., Gareth O. Roberts   +6 more
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Simulation Experiments in Practice: Statistical Design and Regression Analysis [PDF]

In practice, simulation analysts often change only one factor at a time, and use graphical analysis of the resulting Input/Output (I/O) data. Statistical theory proves that more information is obtained when applying Design Of Experiments (DOE) and linear
Kleijnen, J.P.C.
core   +2 more sources

Comparing three approaches to modelling the effects of temperature and rainfall on malaria incidence in different climatic regions

BMC Public Health
Background Malaria transmission is primarily limited to tropical regions where environmental conditions are conducive for the survival of Plasmodium parasites and Anopheles mosquitoes.
Gladstone T. Madito, Basil D. Brooke, Sheetal P. Silal   +2 more
doaj   +1 more source

Managing Macroeconomic Risks by Using Statistical Simulation

Acta Economica et Turistica, 2017
The paper analyzes the possibilities of using statistical simulation in the macroeconomic risks measurement. At the level of the whole world, macroeconomic risks are, due to the excessive imbalance, significantly increased.
Merkaš Zvonko, Perkov Davor, Miličević Petra   +2 more
doaj   +1 more source