Results 111 to 120 of about 1,692,958 (373)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Implementing an Executive-Function Syllabus: Operational Issues [PDF]

Journal of Systemics, Cybernetics and Informatics, 2016
A recent approach to pedagogic challenge, contrastive to the hierarchy approach of Bloom, Anderson, Gagne, Van Hiele, Marzano, Webb and many others, identifies pedagogic challenge with executive function: Pedagogy is defined as challenging if it ...
Russell Jay Hendel
doaj  

Quality of China's Official Statistics: A Brief Review of Academic Perspectives

The Copenhagen Journal of Asian Studies, 2017
Following the rise of the Chinese economy, interest in the official statistics coming from China is intensifying. Official data on GDP, industrial production and other economic indicators attracts a lot of attention all over the world.
Dmitriy Plekhanov
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

The Viability of Topic Modeling to Identify Participant Motivations for Enrolling in Online Professional Development

Online Learning
Identifying motivation for enrollment in MOOCs has been an important way to predict participant success rates. But themes for motivation have largely centered around themes for enrolling in any MOOC, and not ones specific to the course being studied.  In
Heather Allmond Barker, Hollylynne S Lee, Shaun Kellogg, Robin Anderson   +3 more
doaj   +1 more source

Mapping the Field of Statistics Education Research in Search of Scholarship

International Journal for the Scholarship of Teaching and Learning, 2011
This paper is intended as a contribution to the advancement of scholarship in the field of statistics education, which directly links with the scholarship of teaching and learning.
Linda van der Merwe, Annette Wilkinson
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Active-Learning Class Activities and Shiny Applications for Teaching Support Vector Classifiers

Journal of Statistics and Data Science Education
Support vector classifiers are one of the most popular linear classification techniques for binary classification. Different from some commonly seen model fitting criteria in statistics, such as the ordinary least squares criterion and the maximum ...
Qing Wang, Xizhen Cai
doaj   +1 more source

Topics in computational statistics

, 2022
Research in computational statistics develops numerically efficient methods to estimate statistical models, with Monte Carlo algorithms a subset of such methods. This thesis develops novel Monte Carlo methods to solve three important problems in Bayesian statistics.
openaire   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source