Results 111 to 120 of about 2,998,558 (396)

Syntactic Topic Models [PDF]

open access: yesarXiv, 2010
The syntactic topic model (STM) is a Bayesian nonparametric model of language that discovers latent distributions of words (topics) that are both semantically and syntactically coherent. The STM models dependency parsed corpora where sentences are grouped into documents.
arxiv  

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1386-1403, May 2025.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

"Look Ma, No Hands!" A Parameter-Free Topic Model [PDF]

open access: yesarXiv, 2014
It has always been a burden to the users of statistical topic models to predetermine the right number of topics, which is a key parameter of most topic models. Conventionally, automatic selection of this parameter is done through either statistical model selection (e.g., cross-validation, AIC, or BIC) or Bayesian nonparametric models (e.g ...
arxiv  

Anderson localization casts clouds over adiabatic quantum optimization

open access: yes, 2009
Understanding NP-complete problems is a central topic in computer science. This is why adiabatic quantum optimization has attracted so much attention, as it provided a new approach to tackle NP-complete problems using a quantum computer.
Altshuler, Boris   +2 more
core   +2 more sources

Machine learning and conventional statistics: making sense of the differences

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, 2022
Christophe Ley   +5 more
semanticscholar   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Mapping the Academic Landscape of the Renewable Energy Field in Electrical and Electronic Disciplines

open access: yesApplied Sciences, 2020
Research on renewable energy fields of electrical and electronic disciplines is key to promoting the efficient production and utilization of renewable energy, but its branches are numerous and development is uneven.
Wenxiu Xu, Liang Guo, Likai Liang
doaj   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1203-1228, April 2025.
MiR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p microRNAs are downregulated in malignant germ cell tumors (GCTs). Combination replenishment of these microRNAs using mimics resulted in growth inhibition in representative cell lines, with consequent downregulation of target genes involved in cell cycle (confirmed by flow cytometry) and ...
Marta Ferraresso   +12 more
wiley   +1 more source

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