Results 111 to 120 of about 25,871 (229)
Aiqiu Wei,1,* Ziyi Zhong,1,* Yiming Zhang,1 Jincheng He,1 Haihe Pang,2 Xinhua Xia,1 Xiaoqing Zhang1 1School of Pharmacy, Hunan University of Chinese Medicine, Changsha, 410208, People’s Republic of China; 2Hunan Kelun Pharmaceutical Co ...
Wei A +6 more
doaj
Effects of staurosporine on protein kinase C and amylase secretion from pancreatic acini
The effects of staurosporine, a recently isolated microbial alkaloid, on amylase secretion and protein kinase C activity of guinea pig pancreatic acini were investigated.
T. B. Verme +3 more
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Effect of TCERG1 knockdown on the staurosporine-induced apoptotic pathway.
(A) Effect of staurosporine treatment on Jurkat cells. Flow cytometry analysis of Jurkat cells stained with PI without (black) or with the addition of 0.25 (red) or 0.5 μM staurosporine (blue) for 1 h.
Carlos Suñé (812755) +9 more
core +1 more source
Neuroprotection against staurosporine by metalloporphyrins independent of antioxidant capability
Metalloporphyrin catalytic antioxidants are remarkably useful in protecting cells and tissues in a wide array of disease models, attributed primarily to functioning as superoxide dismutase (SOD) mimetics or by scavenging other reactive oxygen species ...
Tauskela, Joseph S., Brunette, Eric
core +1 more source
Tumor necrosis factor (TNF), first described as a cytokine with tumor-necrotizing activity, is now known to be a pleiotropic molecule. The molecular mechanisms responsible for the cytotoxic activity of TNF on malignant cells are still largely unknown. In
Vanhaesebroeck, Bart +8 more
core
An analysis of the time-dependent genetic response to the death-inducer staurosporine was performed in Neurospora crassa by transcriptional profiling.
Ana Castro +13 more
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Staurosporine-Induced Cleavage of α-Smooth Muscle Actin During Myofibroblast Apoptosis
To examine the possibility that staurosporine is applicable for the treatment of abnormal scar formation such as hypertrophic scar and keloid, the cellular process during staurosporine-induced apoptosis was analyzed in myofibroblasts isolated from a rat ...
Toshiyuki Sasaguri +9 more
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Staurosporine induces de novo synthesis of prostaglandin H synthase-2 in rat alveolar macrophages.
This study was initiated to investigate the possible involvement of prostaglandin H synthase in the staurosporine-induced prostaglandin production. The time course of prostaglandin H synthase activity in macrophages treated with staurosporine (20 nM ...
Moon, CH +5 more
core
Staurosporine-related compounds, K252a and UCN-01, inhibit both cPKC and nPKC
The potent inhibitors of protein kinase C (PKC), H7, staurosporine, and staurosporine derivatives, were examined for their inhibitory effects on novel PKC (nPKC) isozymes δ and ε.
Shigeo Ohno +9 more
core +1 more source
Protein kinase-independent inhibition of muscarinic K+ channels by staurosporine
Acetylcholine (ACh) binding to atrial muscarinic receptors activates an inwardly rectifying K+ current (IK[ACh]) via a pertussis toxin-sensitive GTP-binding protein (GK).
G. E. Breitwieser, C. F. Lo
core +1 more source

