Results 111 to 120 of about 27,930 (225)

Caspase-mediated apoptosis, induced by incubation with staurosporine, activates Ob-R shedding mainly mediated by ADAM10.

, 2012
(A) sOb-R levels in the supernatant of Ob-Rfl or Ob-R219.3 transfected cells after incubation with staurosporine (0.1–0.5 µM) or DMSO (0.1%) for 24 h and 48 h.
Ulf Anderegg (168727), Michael Schaab (168705), Juergen Klammt (168715), Juergen Scheller (168741), Marcin Nowicki (109802), Juergen Kratzsch (17112), Henriette Kausch (168709), Stefan Rose-John (53994), Rolf Gebhardt (89997), Joachim Thiery (66414)   +9 more
core   +1 more source

Slowing of the inactivation of voltage-dependent sodium channels by staurosporine, the protein kinase C inhibitor, in rabbit atrial myocytes

, 2006
In this study, the effect of staurosporine, a potent protein kinase C (PKC) inhibitor, on Na+ current (I(Na)) was examined by whole-cell patch recording in rabbit atrial myocytes.
Earm, Yung E., Ko, Jae Hong, Park, Won Sun, Kim, Sung Joon   +3 more
core   +1 more source

Adhesion to type V collagen enhances staurosporine-induced apoptosis of adrenocortical cancer cells

, 2014
Adrenocortical carcinoma (ACC) is a rare and aggressive tumor characterized by poor prognosis and resistance to conventional chemotherapy. Many chemotherapy agents act determining apoptosis, therefore, studying the responsiveness of ACC to apoptosis ...
SCARPA, Susanna, Taglieri, Ludovica, Nardo, Tiziana, Micalizzi, Geraldina, VICINANZA, ROBERTO, DE IULIIS, FRANCESCA   +5 more
core   +1 more source

Simple screening method for staurosporine in bacterial cultures using liquid chromatography-tandem mass spectrometry

, 2009
Staurosporine has been shown to possess an array of important biological properties such as anti-fungal, anti-bacterial, antihypertensive and anti-cancer.
Hewavitharana, A., Fuerst, J. A., Ng, Y. K., Shaw, P. N., Hewavitharana, Amitha, K, Nicholas, P, Amitha K Hewavitharana, Fuerst, John, A, Ng, Yi, K   +8 more
core   +1 more source

Cytoprotective effect of selective small-molecule caspase inhibitors against staurosporine-induced apoptosis

Drug Design, Development and Therapy, 2014
Jianghong Wu, Yuren Wang, Shuguang Liang, Haiching Ma Reaction Biology Corp, Malvern, PA, USA Abstract: Caspases are currently known as the central executioners of the apoptotic pathways.
Wu J, Wang Y, Liang S, Ma H
doaj  

Sensitization of tumor cells to tumor necrosis factor action by the protein kinase inhibitor staurosporine

, 1993
Tumor necrosis factor (TNF), first described as a cytokine with tumor-necrotizing activity, is now known to be a pleiotropic molecule. The molecular mechanisms responsible for the cytotoxic activity of TNF on malignant cells are still largely unknown. In
Vanhaesebroeck, Bart, Schulze-Osthoff, Klaus, Fiers, Walter, De Valck, Dirk, Heyninck, Karen, Boone, Elke, Van Roy, Frans, Beyaert, Rudi, Haegeman, Guy   +8 more
core  

Staurosporine Drives Non-Canonical Melanocyte Maturation by Coupling β-Catenin Signaling to Actin-Dependent Dendrite Remodeling. [PDF]

Pigment Cell Melanoma Res
Xu K, Yang L, Lai S, Yang F, Kuroda Y, Tsuruta D, Katayama I.   +6 more
europepmc   +1 more source

Staurosporine-induced Ca2+ mobilization in rat mandibular salivary acini

, 1998
The effect of the protein kinase C inhibitor, staurosporine, on intracellular Ca2+ homeostasis was investigated in rat mandibular salivary acinar cells loaded with fura-2.
신동민, 서정택
core  

BetaII-spectrin gaps and patches emerge from the patterned assembly of the actin/spectrin membrane skeleton in human motor neuron axons. [PDF]

Elife
Gazal NG, Castellanos-Montiel MJ, Bruno G, Franco-Flores AK, Lépine S, Gursu L, Haghi G, Maussion G, Reintsch WE, Stefani FD, Anastasía A, Bisbal M, Gorostiza EA, Durcan TM, Unsain N.   +14 more
europepmc   +1 more source

Phycocyanobilin: A potential bioactive compound from Arthrospira platensis targeting LYN protein associated with systemic lupus erythematosus. [PDF]

PLoS One
Chaiprasert A, Han P, Laomettachit T, Ruengjitchatchawalya M.   +3 more
europepmc   +1 more source