Results 101 to 110 of about 25,871 (229)

The effect of an HIV-1 viral protease inhibitor on staurosporine-induced apoptosis in immortalized mesangial cells

open access: yesSão Paulo Medical Journal, 2002
CONTEXT: Progressive glomerular sclerosis is a condition characterized by the accumulation of glomerular extracellular matrix and a decrease in the number of glomerular cells.
Adrian Pierce Serone   +2 more
doaj   +1 more source

Simple screening method for staurosporine in bacterial cultures using liquid chromatography-tandem mass spectrometry

open access: yes, 2009
Staurosporine has been shown to possess an array of important biological properties such as anti-fungal, anti-bacterial, antihypertensive and anti-cancer.
Hewavitharana, A.   +3 more
core   +1 more source

Staurosporine Induces ROS-Mediated Process Formation in Human Gingival Fibroblasts and Rat Cortical Astrocytes [PDF]

open access: yes, 2015
In the present study, we investigated the effect of staurosporine on the formation of cellular processes in human gingival fibroblasts and rat astrocytes.
서정택, 강정완, 문성아
core   +1 more source

Effect of Staurosporine on the Intracellular Localization of Hepatitis B Virus Core Protein

open access: yesIndonesian Journal of Biotechnology, 2015
protein is also including in the HBV genome targeting into the nucleus through modulating carboxyl residues byphosphorylation. Nuclear localication Signal (NLS) in HBV core protein is inside the virion structure and it must beunmasked in order to ...
Aris Haryanto   +2 more
doaj  

Release of a leukocyte activation inhibitor by staurosporine-treated pulmonary artery endothelial cells

open access: yes, 1998
Bovine pulmonary arterial endothelial cells (BPAE) treated with the protein kinase C (PKC) inhibitor staurosporine inhibited[Formula: see text] generation by neutrophils exposed to phorbol myristate acetate (PMA) but did not affect[Formula: see text ...
Xilin Chen, John D. Catravas
core   +1 more source

Apoptotic-like activity of staurosporine in axenic cultures of Trypanosoma evansi

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2012
Trypanosoma evansi is a blood protozoan parasite of the genus Trypanosoma which is responsible for surra (Trypanosomosis) in domestic and wild animals. This study addressed apoptotic-like features in Trypanosoma evansi in vitro. The mechanism of parasite
Gustavo Bruges   +4 more
doaj   +1 more source

Staurosporine mobilizes Ca2+ from secretory granules by inhibiting protein kinase C in rat submandibular acinar cells

open access: yes, 2002
Staurosporine was previously shown to mobilize Ca2+ from the thapsigargin-insensitive Ca2+ store in rat submandibular acinar cells. However, the nature of the store is not yet known.
신동민, 이승일, 서정택
core   +1 more source

Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements.

open access: yesPLoS ONE, 2010
Predicting off-targets by computational methods is getting increasing importance in early drug discovery stages. We herewith present a computational method based on binding site three-dimensional comparisons, which prompted us to investigate the cross ...
Enrico Defranchi   +5 more
doaj   +1 more source

Staurosporine overrides checkpoints for mitotic onset in BHK cells.

open access: yes, 1992
Under normal conditions, mammalian cells will not initiate mitosis in the presence of either unreplicated or damaged DNA. We report here that staurosporine, a tumor promoter and potent protein kinase inhibitor, can uncouple mitosis from the completion of
Tam, S. W., Schlegel, R.
core  

Involvement of mitochondrial proteins in calcium signaling and cell death induced by staurosporine in Neurospora crassa

open access: yes, 2015
Staurosporine-induced cell death in Neurospora crassa includes a well defined sequence of alterations in cytosolic calcium levels, comprising extracellular Ca2 + influx and mobilization of Ca2 + from internal stores.
Correia-de-Sá, Paulo   +5 more
core   +2 more sources

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