Results 101 to 110 of about 27,930 (225)

Apoptotic-like activity of staurosporine in axenic cultures of Trypanosoma evansi

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2012
Trypanosoma evansi is a blood protozoan parasite of the genus Trypanosoma which is responsible for surra (Trypanosomosis) in domestic and wild animals. This study addressed apoptotic-like features in Trypanosoma evansi in vitro. The mechanism of parasite
Gustavo Bruges   +4 more
doaj   +1 more source

Modulation of macrophage scavenger receptor transport by protein phosphorylation

open access: yesJournal of Lipid Research, 1996
The identification of three highly conserved phosphorylation sites in the cytoplasmic domain of each of the monomeric subunits of the macrophage scavenger receptor suggests that protein phosphorylation may regulate this receptor pathway.
L G Fong
doaj   +1 more source

Methylation of histone H3 lysine 27 associated with apoptosis in osteosarcoma cells induced by staurosporine [PDF]

open access: yes, 2009
The relationship between histone methylation and apoptosis, programmed cell death, is beginning to be explored. The objective of this study was to investigate the effects of staurosporine, a PKC inhibitor on the methylation of histone H3 in ...
Lee, Herng-Sheng   +4 more
core  

Effects of staurosporine on protein kinase C and amylase secretion from pancreatic acini

open access: yes, 1989
The effects of staurosporine, a recently isolated microbial alkaloid, on amylase secretion and protein kinase C activity of guinea pig pancreatic acini were investigated.
T. B. Verme   +3 more
core   +1 more source

Release of a leukocyte activation inhibitor by staurosporine-treated pulmonary artery endothelial cells

open access: yes, 1998
Bovine pulmonary arterial endothelial cells (BPAE) treated with the protein kinase C (PKC) inhibitor staurosporine inhibited[Formula: see text] generation by neutrophils exposed to phorbol myristate acetate (PMA) but did not affect[Formula: see text ...
Xilin Chen, John D. Catravas
core   +1 more source

Staurosporine overrides checkpoints for mitotic onset in BHK cells.

open access: yes, 1992
Under normal conditions, mammalian cells will not initiate mitosis in the presence of either unreplicated or damaged DNA. We report here that staurosporine, a tumor promoter and potent protein kinase inhibitor, can uncouple mitosis from the completion of
Tam, S. W., Schlegel, R.
core  

Modulation of fungal sensitivity to staurosporine by targeting proteins identified by transcriptional profiling

open access: yes, 2011
An analysis of the time-dependent genetic response to the death-inducer staurosporine was performed in Neurospora crassa by transcriptional profiling.
Ana Castro   +13 more
core   +1 more source

A Concise Synthesis of rac-Staurosporine Glycon

open access: yes, 2016
A Concise Synthesis of rac-Staurosporine ...
Fen-Ling Liao (2717692)   +3 more
core   +1 more source

Synergism between staurosporine and drugs inducing endoplasmic reticulum stress

open access: yes, 2006
Drugs causing endoplasmic reticulum or mitochondrial dysfunction may trigger apoptosis in eukaryotic cells. The thiol reagent dithiothreitol (DTT) belongs to the first group whereas the protein kinases inhibitor staurosporine acts on mitochondria.
TREVISI, LUCIA   +7 more
core   +1 more source

Effect of recombinant exendin-4 on proliferation and staurosporine-induced apoptosis of INS-1 cells.

open access: yes, 2016
(a) INS-1 cells were preincubated with media alone or with 100 nmol/l wortmannin, followed by treatment with different agents as indicated for 18 h (means ± SD, n = 3). *p 0.05 vs. control cells with pure cell media; ##p 0.01.
Rui Yu (296180)   +6 more
core   +1 more source

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