Results 81 to 90 of about 27,930 (225)
Oomycetes are devastating soil-borne plant pathogens, and cause numerous losses on diverse crops worldwide. In this study, our aim was to identify actinomycetes with antimicrobial activity towards oomycetes from the rhizosphere of soybean.
Lihui Wei (511898) +14 more
core +1 more source
Biosynthetic studies of staurosporine and metabolism studies of Streptomyces staurosporeus.
Biosynthetic studies of staurosporine and metabolism studies of Streptomyces ...
Shu-Wei. Yang (7958228)
core +2 more sources
Sulfonamide–thiazolidinone hybrids integrate complementary pharmacophores to generate multifunctional scaffolds with broad pharmacological potential. Their structural versatility supports antimicrobial, antifungal, antioxidant, anticancer, anti‐inflammatory, antidiabetic, anticonvulsant, and enzyme‐inhibitory activities.
Subham Kumar Vishwakarma +6 more
wiley +1 more source
Combinations of 5‐Fluorouracil with UCN‐01 or Staurosporine
AbstractFor Abstract see ChemInform Abstract in Full Text.
Sigmond, J. +3 more
openaire +3 more sources
Staurosporine blocks evoked release of FM1-43 but not acetylcholine from frog motor nerve terminals
The protein kinase inhibitor staurosporine inhibited, and often abolished, activity-dependent destaining of frog motor nerve terminals that had been preloaded with the fluorescent dye FM1-43.
WJ Betz, AW Henkel
core +1 more source
Staurosporine-induced cell death in Neurospora crassa includes a well defined sequence of alterations in cytosolic calcium levels, comprising extracellular Ca2 + influx and mobilization of Ca2 + from internal stores.
Correia-de-Sá, Paulo +5 more
core +2 more sources
The motility of zoospores is critical in the disease cycles of Peronosporomycetes that cause devastating diseases in plants, fishes, vertebrates, and microbes.
Md. Tofazzal Islam +2 more
doaj +1 more source
Total Synthesis of (+)-RK-286c, (+)-MLR-52, (+)-Staurosporine, and (+)-K252a
Total Synthesis of (+)-RK-286c, (+)-MLR-52, (+)-Staurosporine, and ...
Brian M. Stoltz (1297560) +2 more
core +1 more source
Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley +1 more source
On the origins of enzyme inhibitor selectivity and promiscuity: a case study of protein kinase binding to staurosporine [PDF]
Protein kinases are important regulatory enzymes in signal transduction and in cell regulation. Understanding inhibition mechanisms of kinases is important for the further development of new therapies for cancer and inflammatory diseases.
William R. Pitt +3 more
core +2 more sources

