Results 81 to 90 of about 27,930 (225)

Staurosporine-producing Streptomyces sp. strain 11 × 1 cell-free culture filtrates control diseases caused by the oomycete plant pathogens Pythium myriotylum and Phytophthora sojae

open access: yes
Oomycetes are devastating soil-borne plant pathogens, and cause numerous losses on diverse crops worldwide. In this study, our aim was to identify actinomycetes with antimicrobial activity towards oomycetes from the rhizosphere of soybean.
Lihui Wei (511898)   +14 more
core   +1 more source

Biosynthetic studies of staurosporine and metabolism studies of Streptomyces staurosporeus.

open access: yes, 1997
Biosynthetic studies of staurosporine and metabolism studies of Streptomyces ...
Shu-Wei. Yang (7958228)
core   +2 more sources

4‐Thiazolidinone/2,4‐Thiazolidinedione–Sulfonamide Hybrids: A Concise Review of Their Design and Pharmacological Significance

open access: yesChemMedChem, Volume 21, Issue 20, 28 October 2026.
Sulfonamide–thiazolidinone hybrids integrate complementary pharmacophores to generate multifunctional scaffolds with broad pharmacological potential. Their structural versatility supports antimicrobial, antifungal, antioxidant, anticancer, anti‐inflammatory, antidiabetic, anticonvulsant, and enzyme‐inhibitory activities.
Subham Kumar Vishwakarma   +6 more
wiley   +1 more source

Combinations of 5‐Fluorouracil with UCN‐01 or Staurosporine

open access: yesChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Sigmond, J.   +3 more
openaire   +3 more sources

Staurosporine blocks evoked release of FM1-43 but not acetylcholine from frog motor nerve terminals

open access: yes, 1995
The protein kinase inhibitor staurosporine inhibited, and often abolished, activity-dependent destaining of frog motor nerve terminals that had been preloaded with the fluorescent dye FM1-43.
WJ Betz, AW Henkel
core   +1 more source

Involvement of mitochondrial proteins in calcium signaling and cell death induced by staurosporine in Neurospora crassa

open access: yes, 2015
Staurosporine-induced cell death in Neurospora crassa includes a well defined sequence of alterations in cytosolic calcium levels, comprising extracellular Ca2 + influx and mobilization of Ca2 + from internal stores.
Correia-de-Sá, Paulo   +5 more
core   +2 more sources

Protein Kinase C Is Likely to be Involved in Zoosporogenesis and Maintenance of Flagellar Motility in the Peronosporomycete Zoospores

open access: yesMolecular Plant-Microbe Interactions, 2011
The motility of zoospores is critical in the disease cycles of Peronosporomycetes that cause devastating diseases in plants, fishes, vertebrates, and microbes.
Md. Tofazzal Islam   +2 more
doaj   +1 more source

Total Synthesis of (+)-RK-286c, (+)-MLR-52, (+)-Staurosporine, and (+)-K252a

open access: yes, 2016
Total Synthesis of (+)-RK-286c, (+)-MLR-52, (+)-Staurosporine, and ...
Brian M. Stoltz (1297560)   +2 more
core   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

open access: yesAdvanced Science, Volume 13, Issue 59, 23 October 2026.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

On the origins of enzyme inhibitor selectivity and promiscuity: a case study of protein kinase binding to staurosporine [PDF]

open access: yes, 2009
Protein kinases are important regulatory enzymes in signal transduction and in cell regulation. Understanding inhibition mechanisms of kinases is important for the further development of new therapies for cancer and inflammatory diseases.
William R. Pitt   +3 more
core   +2 more sources

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