Results 91 to 100 of about 27,930 (225)

Staurosporine induces de novo synthesis of prostaglandin H synthase-2 in rat alveolar macrophages.

, 1995
This study was initiated to investigate the possible involvement of prostaglandin H synthase in the staurosporine-induced prostaglandin production. The time course of prostaglandin H synthase activity in macrophages treated with staurosporine (20 nM ...
Moon, CH, Lee, SH, Kim, MJ, Kim, JY, Moon, CK, Lee, JY   +5 more
core   +1 more source

Staurosporine as a Potential Treatment for Acanthamoeba Keratitis Using Mouse Cornea as an Ex Vivo Model

Marine Drugs
Acanthamoeba is a ubiquitous genus of amoebae that can trigger a severe and progressive ocular disease known as Acanthamoeba Keratitis (AK). Furthermore, current treatment protocols are based on the combination of different compounds that are not fully ...
Rubén L. Rodríguez-Expósito, Ines Sifaoui, Lizbeth Salazar-Villatoro, Carlos J. Bethencourt-Estrella, José J. Fernández, Ana R. Díaz-Marrero, Robert Sutak, Maritza Omaña-Molina, José E. Piñero, Jacob Lorenzo-Morales   +9 more
doaj   +1 more source

INDUCTION OF STABLE LONG-TERM POTENTIATION IN THE PRESENCE OF THE PROTEIN-KINASE-C ANTAGONIST STAUROSPORINE

, 1992
We have studied the effects of staurosporine, an antagonist of the catalytic subunit of protein kinase C, on the mechanisms of long-term potentiation (LTP) in rat hippocampal slices maintained in vitro.
BITTAR, P, Boddeke, H., BODDEKE, H, Bittar, P., Muller, Dominique, MULLER, D, Bittar P, Boddeke H, Muller D   +8 more
core   +2 more sources

Staurosporine, a protein kinase inhibitor, activates K-Cl cotransport in LK sheep erythrocytes

, 1994
K-Cl cotransport can participate in volume regulation in a number of cell types. Swelling activation of K-Cl cotransport in sheep erythrocytes proceeds by a two-step process, A<-->B<-->C (Dunham et al., J. Gen. Physiol.
P. B. Dunham, I. Bize
core   +1 more source

Raising intracellular calcium attenuates neuronal apoptosis triggered by staurosporine or oxygen-glucose deprivation in the presence of glutamate receptor blockade

Neurobiology of Disease, 2004
The relationship between intracellular Ca2+ ([Ca2+]i) regulation and programmed cell death is not well-defined; both increases and decreases in [Ca2+]i have been observed in cells undergoing apoptosis.
Lorella M.T Canzoniero, Debra J Babcock, Frank J Gottron, Margaret C Grabb, Pat Manzerra, B.Joy Snider, Dennis W Choi   +6 more
doaj   +1 more source

Structure determination and refinement of RTKC8 kinase domain bound to staurosporine.

, 2023
Structure determination and refinement of RTKC8 kinase domain bound to staurosporine.
Teena Bajaj (6828443), John Kuriyan (14696), Christine L. Gee (331015)   +2 more
core   +1 more source

The effect of an HIV-1 viral protease inhibitor on staurosporine-induced apoptosis in immortalized mesangial cells

São Paulo Medical Journal, 2002
CONTEXT: Progressive glomerular sclerosis is a condition characterized by the accumulation of glomerular extracellular matrix and a decrease in the number of glomerular cells.
Adrian Pierce Serone, Simone Mafalda Rodrigues Camargo, Nestor Schor   +2 more
doaj   +1 more source

Staurosporine Inhibits Frequency-Dependent Myofilament Desensitization in Intact Rabbit Cardiac Trabeculae

Biochemistry Research International, 2012
Myofilament calcium sensitivity decreases with frequency in intact healthy rabbit trabeculae and associates with Troponin I and Myosin light chain-2 phosphorylation.
Kenneth D. Varian, Brandon J. Biesiadecki, Mark T. Ziolo, Jonathan P. Davis, Paul M. L. Janssen   +4 more
doaj   +1 more source

Aptamer-Mediated Dual-Loaded Liposomal Nanosystem for Synergistic Therapy in Hepatocellular Carcinoma via mTOR/HIF-1&alpha;/VEGF Pathway

International Journal of Nanomedicine
Aiqiu Wei,1,&ast; Ziyi Zhong,1,&ast; Yiming Zhang,1 Jincheng He,1 Haihe Pang,2 Xinhua Xia,1 Xiaoqing Zhang1 1School of Pharmacy, Hunan University of Chinese Medicine, Changsha, 410208, People’s Republic of China; 2Hunan Kelun Pharmaceutical Co ...
Wei A, Zhong Z, Zhang Y, He J, Pang H, Xia X, Zhang X   +6 more
doaj  

Effect of Staurosporine on the Intracellular Localization of Hepatitis B Virus Core Protein

Indonesian Journal of Biotechnology, 2015
protein is also including in the HBV genome targeting into the nucleus through modulating carboxyl residues byphosphorylation. Nuclear localication Signal (NLS) in HBV core protein is inside the virion structure and it must beunmasked in order to ...
Aris Haryanto, Nastiti Wijayanti, Michael Kann   +2 more
doaj