Results 151 to 160 of about 25,920 (226)

4-Hydroxybutyrate (4HB) released from poly-4-hydroxybutyrate scaffolds does not impact hallmark phenotypes of cancer in malignant or non-malignant breast cells. [PDF]

Breast Cancer Res
Elahi SF, Martin DP, Wan Y, Zhang L, Romero DJ, Kommeri R, Cramer MC, Reavie L, Mercer AC, Ardila DC, Hussey GS, Badylak SF.   +11 more
europepmc   +1 more source

A comprehensive pharmacological survey across heterogeneous patient-derived glioblastoma stem cell models. [PDF]

iScience
Elliott RJR, Nagle PWK, Furqan M, Dawson JC, Smer-Barreto V, Oyarzún DA, McCarthy A, Munro AF, Drake C, Morrison GM, Pollard SM, Marand M, Ebner D, Brunton VG, Frame MC, Carragher NO.   +15 more
europepmc   +1 more source

Immunomodulating effects of herbal cough medication - in vitro screening in a TLR7- and TLR8-mediated inflammatory model. [PDF]

BMC Complement Med Ther
Voigts J, Niederreiter L, Huber R, Kowarschik S.   +3 more
europepmc   +1 more source

Potent, Selective Pyrrolopyrimidine PDE11A4 Inhibitors with Improved Pharmaceutical Properties. [PDF]

ACS Med Chem Lett
Mahmood SU, Boddu RK, Eberhard J, Hoffman CS, Gordon J, Colussi D, Childers W, Amurrio E, Danaher M, Kelly MP, Rotella DP.   +10 more
europepmc   +1 more source

A missense mutation in acyl-CoA synthetase ACSL4 reveals essential residues for catalytic activity in ferroptosis. [PDF]

J Biol Chem
Sei H, Ando H, Nakashima F, Takahara T, Kita M, Yamada KI, Uchida K, Shibata T.   +7 more
europepmc   +1 more source

Rikkunshito ameliorates colonic dysfunction and hormonal imbalance in an IBS mouse model with modulation of transient receptor potential channel activity. [PDF]

Front Pharmacol
Choi WG, Choi NR, Jung D, Kim SC, Woo JH, Kim BJ.   +5 more
europepmc   +1 more source

Indolocarbazoles as host-directed therapeutics against intracellular infections by methicillin-resistant Staphylococcus aureus. [PDF]

J Antimicrob Chemother
van den Biggelaar RHGA, Erdkamp D, de Visser AW, van den Eeden SJF, Saris A.   +4 more
europepmc   +1 more source

Chloride Intracellular Channel 4 (CLIC4) controls volume regulation in sperm development via Protein Kinase C (PKC). [PDF]

BMC Biol
Loyo-Celis V, Sanghvi S, Raut SK, Castillo HP, de la Vega Beltran JL, Orta G, Montanez-Barragan A, Patel A, Amaro VXA, Rao SG, Edwards JC, Partida-Sanchez S, Darszon A, Guerrero A, Singh H.   +14 more
europepmc   +1 more source

Protocol to study direct (de)phosphorylation events on a proteome-wide scale using on-bead in vitro enzyme assays. [PDF]

STAR Protoc
Brunner M, Hu Z, Caligaris M, Stumpe M, De Virgilio C, Dengjel J.   +5 more
europepmc   +1 more source

Development, anti-proliferative activity, multi-target kinase inhibition against CHK1, PIM1, and CDK-2, and computational insights of new thiazole-based hybrids. [PDF]

RSC Adv
Altwaijry NA, Othman IMM, Anwar MM, Nosier SS, Saleh A, Tashkandi NY, Nossier ES.   +6 more
europepmc   +1 more source