Results 161 to 170 of about 27,930 (225)

Reverse engineering of BNIP3 identifies a mitochondrial protective peptide. [PDF]

Nat Commun
Hendgen-Cotta UB, Roth A, Beuck C, Messiha D, Settelmeier S, Shah SB, Korste S, Bravo-Rodriguez K, Blueggel M, Cansiz F, Martins Nascentes Melo L, Roesler J, Meckelmann SW, Schmitz OJ, Kaschani F, Kaiser M, Esfeld S, El Bounkari O, Bernhagen J, Brameyer S, Jung K, Schmitt LI, Leo M, Hagenacker T, Totzeck M, Minor T, Ehrmann M, Tasdogan A, Bayer P, Rassaf T.   +29 more
europepmc   +1 more source

In Vitro and In Silico Evaluation of the Antitumor Potential of New Benzotriazole-1,2,4-Triazole Hybrids. [PDF]

Pharmaceuticals (Basel)
Mardale G, Dumitrașcu V, Pop R, Dumitru C, Muntean D, Mioc M, Mioc A, Mara BI, Balan-Porcarasu M, Budu O, Negrea-Ghiulai R, Șoica C.   +11 more
europepmc   +1 more source

Benzimidazole derivatives as dual EGFR and BRAF^V600E inhibitors with pro-apoptotic antiproliferative potential. [PDF]

RSC Adv
Al-Wahaibi LH, Samir M, Bräse S, Youssif BGM, Morcoss MM.   +4 more
europepmc   +1 more source

Inertial sensing of water content in tumor spheroids. [PDF]

Sci Adv
Katsikis G, Yoon JC, Usherwood TR, Malinowski S, Yu J, Chen C, Son S, Sutton JL, Ligon KL, Lee J, Miettinen TP, Manalis SR.   +11 more
europepmc   +1 more source

A meta learning and task adaptive approach for drug target affinity prediction. [PDF]

Nat Commun
Wan M, Zhao Y, Zhang Y, Xu H, Yi D, Zan P, He S, Bo X.   +7 more
europepmc   +1 more source

Hemin suppresses interferon responses in periodontal cell models through JAK2-STAT1 inhibition. [PDF]

Front Immunol
Huang X, Gruber R, Panahipour L.
europepmc   +1 more source

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ChemInform Abstract: First Total Synthesis of Staurosporine and ent‐Staurosporine.

ChemInform, 1995
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
J. T. LINK, S. RAGHAVAN, S. J. DANISHEFSKY   +2 more
openaire   +1 more source

Inhibition of aldosterone biosynthesis by staurosporine

Biological Chemistry, 2005
AbstractStaurosporine (STS) is a very potent broad-range kinase inhibitor, and its antiproliferative properties made it a lead compound for protein kinase C (PKC) inhibitors with therapeutic potential. Because STS also causes hypotension, we investigated in this study whether it directly interferes with the terminal steps of aldosterone biosynthesis ...
Matthias, Bureik, Alexander, Mion, Christopher J, Kenyon, Rita, Bernhardt   +3 more
openaire   +2 more sources

Synthesis of the staurosporine aglycone

Journal of the Chemical Society, Chemical Communications, 1990
The staurosporine aglycone 3 has been synthesised in 22.6% overall yield from ethyl indole-2-acetate by a route which involves an intramolecular Diels–Alder reaction of the pyranoindolone 8 followed by nitrene mediated cyclisation.
Christopher J. Moody, Kulsum F. Rahimtoola   +1 more
openaire   +1 more source