Results 71 to 80 of about 2,668,180 (336)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Simulating a Steady-state Heliosphere
The Astrophysical Journal Supplement SeriesEver since the discovery of the solar wind, it has been understood that our solar system resides within a bubble of solar wind plasma that originates from the Sun.
Jacob Heerikhuisen +2 more
doaj +1 more source
Non-equilibrium steady state of sparse systems
, 2011 A resistor-network picture of transitions is appropriate for the study of energy absorption by weakly chaotic or weakly interacting driven systems. Such "sparse" systems reach a novel non-equilibrium steady state (NESS) once coupled to a bath.
Cohen D. +9 more
core +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Steady State of microemulsions in shear flow
, 2000 Steady-state properties of microemulsions in shear flow are studied in the context of a Ginzburg-Landau free-energy approach. Explicit expressions are given for the structure factor and the time correlation function at the one loop level of approximation.
A. Cappi +28 more
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Steady-State Creep of Asphalt Concrete
Applied Sciences, 2017 This paper reports the experimental investigation of the steady-state creep process for fine-grained asphalt concrete at a temperature of 20 ± 2 °С and under stress from 0.055 to 0.311 MPa under direct tension and was found to occur at a constant rate ...
Alibai Iskakbayev +2 more
doaj +1 more source
Metabolic Flux Analysis—Linking Isotope Labeling and Metabolic Fluxes
Metabolites, 2020 Metabolic flux analysis (MFA) is an increasingly important tool to study metabolism quantitatively. Unlike the concentrations of metabolites, the fluxes, which are the rates at which intracellular metabolites interconvert, are not directly measurable ...
Yujue Wang +4 more
doaj +1 more source
Gibbs phenomenon and the emergence of the steady-state in quantum transport
, 2019 Simulations are increasingly employing explicit reservoirs - internal, finite regions - to drive electronic or particle transport. This naturally occurs in simulations of transport via ultracold atomic gases.
Zwolak, Michael
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source