Results 71 to 80 of about 538,729 (318)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Transportation Engineering, 2020 The combustion process of the Engine Combustion Network (ECN) Spray A and Spray D is studied over a wide range of ambient temperatures from 750 K to 900 K.
J.M. García-Oliver +3 more
doaj +1 more source
Transient Combustion Analysis for Iron Micro-Particles in a Gaseous Oxidizing Medium Using Adomian Decomposition Method [PDF]
Computational Engineering and Physical Modeling, 2018 The present study presents analytical solution to transient combustion analysis for iron micro-particles in a gaseous oxidizing medium using Adomian decomposition method.
Gbeminiyi Sobamowo, Ahmed Yinusa
doaj +1 more source
Thermal oscillations in the decomposition of organic peroxides: Identification of a hazard, utilization, and suppression [PDF]
, 2016 The purpose of this research is to identify and characterize oscillatory thermal instability in organic peroxides that are used in vast quantities in industry and misused by terrorists.
Ball, Rowena
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Chemical sensitivity to the ratio of the cosmic-ray ionization rates of He and H2 in dense clouds [PDF]
, 2006 Aim: To determine whether or not gas-phase chemical models with homogeneous and time-independent physical conditions explain the many observed molecular abundances in astrophysical sources, it is crucial to estimate the uncertainties in the calculated ...
Baldwin +24 more
core +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
, 2007 Toric dynamical systems are known as complex balancing mass action systems in the mathematical chemistry literature, where many of their remarkable properties have been established.
Craciun, Gheorghe +3 more
core
Photochemistry in the arctic free troposphere: NOx budget and the role of odd nitrogen reservoir recycling [PDF]
, 2003 The budget of nitrogen oxides (NOx) in the arctic free troposphere is calculated with a constrained photochemical box model using aircraft observations from the Tropospheric O3 Production about the Spring Equinox (TOPSE) campaign between February and May.
Atlas, E +13 more
core +1 more source