Results 41 to 50 of about 17,469 (301)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Effects of steaming and drying for nine times on the quality of Polygonatum cyrtonema from Jiuhua Mountain [PDF]
Zhongguo niangzaoIn order to study the effects of different steaming and drying times on the active components, taste and antioxidant activity of Polygonatum sibiricum from Jiuhua Mountain, the changes of sensory quality, extracts, active components, volatile components,
LUO Xin, HU Yang, NI Xingting, TAN Xiaofei, HUANG Nie, LAI Fuli, LI Qiang, YANG Qiang
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Decision Making Between Full Speed, Slow Steaming, Extra Slow Steaming And Super Slow Steaming By Using Topsis [PDF]
, 2017 Many shipping companies were trying to deliver their cargoes as quickly and reliably as possible. But in the beginning of the latest economic crisis on 2007, the containership fleet is slowing down.
Lubnan, Mizan
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Analysis of Steaming Solution Obtained by the Steaming Treatment of Sugi (Cryptomeria japonica) Wood [PDF]
, 2004 The amounts of phenolics, flavanols and tannins in the steaming solution which was obtained by the streaming treatment of Sugi wood at 150 ℃ for 30-180 min were increased with a lengthening of the steaming time.
Sugamoto, Kazuhiro +17 more
core
FoodsAs a culturally iconic Chinese delicacy, pufferfish lacks systematic research on thermal processing optimization and pre-cooked meal development, limiting its industrial standardization and quality preservation.
Zhihui Liu +11 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to validate the Pediatric Arthritis Ultrasound Scoring System (PAUSS) for upper extremity joints in children with juvenile idiopathic arthritis (JIA). Methods Children with JIA were evaluated for elbow, wrist, or finger arthritis by clinical examination (CE) and musculoskeletal ultrasound (MSUS) with images scored according to the ...
Patricia Vega‐Fernandez +12 more
wiley +1 more source