Results 161 to 170 of about 170,525 (342)

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

Liver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono, Riccardo De Carlis, Alessandro Gambella, Francesca Farnesi, Alice Podestà, Andrea Lauterio, Francesco Tandoi, Luciano De Carlis, Renato Romagnoli   +8 more
wiley   +1 more source

Corrigendum to “An updated meta-analysis of pioglitazone exposure and bladder cancer and comparison to the drug’s effect on cardiovascular disease and non-alcoholic steatohepatitis” [Diab. Res. Clin. Pract. 135 (2018) 102–110] [PDF]

, 2018
Mayer B. Davidson, Deyu Pan
openalex   +1 more source

A Fast Path from Innovation to Safe and Effective Medicines

Clinical Pharmacology &Therapeutics, EarlyView.
Consistent progress in medicines development has allowed both for de novo treatment options and for the refinement of existing products that improve effectiveness or reduce harm. Nonetheless, unmet medical needs persist, particularly in rare diseases, pediatrics and underserved populations.
Peter Arlett, Falk Ehmann, Ralf Herold, Evdokia Korakianiti, Pierpaolo Moscariello, Liese Barbier, Iordanis Gravanis, Frank Pétavy, Emmanuel Cormier, Andrew Thomson, Spiros Vamvakas, Steffen Thirstrup   +11 more
wiley   +1 more source

Influence of antidysbiotic drugs on the liver of rats with experimental non-alcoholic steatohepatitis

Journal of Education, Health and Sport, 2017
High-fat diets combined with the introduction of lincomycin causes the development of steatohepatitis. Introduction antidysbiotic drugs (pro- and prebiotics) has a therapeutic effect.
A. P. Levitsky, V. L. Vasjuk, E. M. Levchenko   +2 more
doaj  

Gallic acid mitigates high-fat and high-carbohydrate diet-induced steatohepatitis by modulating the IRF6/PPARγ signaling pathway

Frontiers in Pharmacology
Gallic acid (GA), a natural organic phenolic compound, is an abundant plant food bioactive substance present in many medicinal herbs. GA has anti-oxidative, anti-inflammatory and anticancer activities on multiple metabolic disorders.
Jiahao Qiu, Jiahao Qiu, Lihong Fu, Yan Xue, Yan Xue, Yilan Yang, Fengjie Qiao, Wanchun Zhu, Yating Gao, Miao Fang, Yufei Liu, Zhujun Gao, Yunfeng Guan, Yunfeng Guan, Yueqiu Gao, Yueqiu Gao, Yueqiu Gao, Xin Zhang, Zhi Shang, Zhi Shang, Zhi Shang   +20 more
doaj   +1 more source

Liver stiffness measurement for non‐invasive assessment of central venous pressure in patients with heart failure: A multicentre pilot study

European Journal of Heart Failure, EarlyView.
Liver stiffness measurement for central venous pressure assessment. AUC, area under the curve; BMI, body mass index; CI, confidence interval; CVP, central venous pressure; HF, heart failure; LSM, liver stiffness measurement; LVEF, left ventricular ejection fraction. Abstract Aims Central venous pressure (CVP) is an important variable in assessing heart
Nicolas Girerd, Jan Biegus, Adam Janas, Piotr Buszman, Marcin Suska, Ovidiu Chioncel, Julie Foucquier, Anne Llorca, Laura Cantu Sanchez, Marat Fudim, Kevin Damman, Maria Rosa Costanzo, Beth Davison, Gad Cotter, Laurent Sandrin, Victor de Lédinghen, Alexandre Mebazaa   +16 more
wiley   +1 more source

Technical acoustic measurements combined with clinical parameters for differential diagnosis of nonalcoholic steatohepatitis [PDF]

, 2023
Yanan Zhao, Chen Qiu, Yiping Dong, Xuchu Wang, Jifan Chen, Jianting Yao, Yifan Jiang, Chao Zhang, Huifang Weng, Yajing Liu, Yik Ning Wong, Pintong Huang   +11 more
openalex   +1 more source

Incidence of major cardiovascular events in patients with metabolic dysfunction‐associated steatotic liver disease in the general population

European Journal of Heart Failure, EarlyView.
Aims Major adverse cardiovascular events (MACE) related to cardiovascular disease are a major cause of death in patients with metabolic dysfunction‐associated steatotic liver disease (MASLD). We explored the impact of MASLD on incident MACE and overall mortality in the general population in Germany.
Yvonne Huber, Lea Hofmann, Jürgen H. Prochaska, Thomas Koeck, Julian Chalabi, Norbert Pfeiffer, Manfred Beutel, Konstantin Strauch, Karl J. Lackner, Oliver Tüscher, Thomas Münzel, Matthias M. Weber, Julia Weinmann‐Menke, Philipp Wild, Peter R. Galle, Jörn M. Schattenberg   +15 more
wiley   +1 more source

Management and Modification of Flavonoids Against Nonalcoholic Fatty Liver Disease

Food Bioengineering, EarlyView.
Flavonoids protect against NAFLD by enhancing mitochondrial function, reducing ER stress, and modulating gut microbiota. Structural modifications improve flavonoid efficacy, offering a promising dietary strategy for NAFLD management. ABSTRACT Flavonoids are small bioactive molecules commonly found in plant‐derived foods, exhibiting antioxidant, anti ...
Weidong Bai, Bingqi Huang, Wenhong Zhao, Gongliang Liu, Limei Yu, Zhi Lu, Hong Wang   +6 more
wiley   +1 more source

Lactobacillus helveticus ZJUIDS12 Rescues Alcohol‐Associated Liver Disease via a Clostridium butyricum‐Regulated Intestinal Reg3γ Pathway

Food Frontiers, EarlyView.
Lactobacillus helveticus ZJUIDS12 rescues alcohol‐associated liver disease via a Clostridium butyricum‐regulated intestinal Reg3γ pathway. ABSTRACT Alcohol‐associated liver disease (ALD) has become a serious public health issue worldwide. This study was conducted to investigate the protective role of Lactobacillus helveticus ZJUIDS12 (Z12) on ALD. Z12 (
Qinchao Ding, Feiwei Cao, Shanglei Lai, Jundi Yu, Yibo Zeng, Teresa G. Valencak, Shuo Zhang, Xiu Zhang, Xiaobing Dou, Songtao Li, Daxi Ren   +10 more
wiley   +1 more source