Results 61 to 70 of about 96,164 (192)

Gallic acid mitigates high-fat and high-carbohydrate diet-induced steatohepatitis by modulating the IRF6/PPARγ signaling pathway

Frontiers in Pharmacology
Gallic acid (GA), a natural organic phenolic compound, is an abundant plant food bioactive substance present in many medicinal herbs. GA has anti-oxidative, anti-inflammatory and anticancer activities on multiple metabolic disorders.
Jiahao Qiu, Jiahao Qiu, Lihong Fu, Yan Xue, Yan Xue, Yilan Yang, Fengjie Qiao, Wanchun Zhu, Yating Gao, Miao Fang, Yufei Liu, Zhujun Gao, Yunfeng Guan, Yunfeng Guan, Yueqiu Gao, Yueqiu Gao, Yueqiu Gao, Xin Zhang, Zhi Shang, Zhi Shang, Zhi Shang   +20 more
doaj   +1 more source

Osteoprotegerin deficiency aggravates methionine- choline- deficient diet-induced nonalcoholic steatohepatitis in mice [PDF]

, 2022
Shaobo Wu, Yao Wu, Lan Lin, Changshun Ruan, Fang Li, Rong Chen, Hongxin Du, Xianxiang Zhang, Xiaohe Luo   +8 more
openalex   +1 more source

Signaling in Simple Steatosis and Non-alcoholic Steatohepatitis Cirrhosis: TGF-β1, YAP/TAZ, and Hedgehog Pathway Activity [PDF]

, 2018
Sina Mohagheghi, Zohreh Khajehahmadi, Heidar Tavilani   +2 more
openalex   +1 more source

Letter: diagnostic accuracy of M30 levels for identifying patients with non‐alcoholic steatohepatitis [PDF]

, 2012
Yusuf Yılmaz
openalex   +1 more source

Alcoholic liver disease: State-of-the-art

Терапевтический архив, 2014
The literature review gives the present views of the diagnosis and treatment of alcoholic liver disease (ALD) and data on the genetic markers associated with the development of ALD and alcohol addiction.
I V Maev, D T Abdurakhmanov, D N Andreev, D T Dicheva   +3 more
doaj  

Reduced Lysosomal Acidification Induce p53 and Unfolded Protein Response in Mice With Nutritional Steatohepatitis [PDF]

, 2015
Xiaojuan Wang, William Ka Kei Wu, Chi Hin Cho, Joseph J.�Y. Sung, Jun Yu   +4 more
openalex   +1 more source

Therapeutic implications for sphingolipid metabolism in metabolic dysfunction-associated steatohepatitis

Frontiers in Endocrinology
The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), a leading cause of chronic liver disease, has increased worldwide along with the epidemics of obesity and related dysmetabolic conditions characterized by impaired ...
Bruno Ramos-Molina, Joana Rossell, Joana Rossell, Alejandra Pérez-Montes de Oca, Eva Pardina, Idoia Genua, Marina I. Rojo-López, María Teresa Julián, Núria Alonso, Núria Alonso, Josep Julve, Josep Julve, Didac Mauricio, Didac Mauricio, Didac Mauricio, Didac Mauricio, Didac Mauricio   +16 more
doaj   +1 more source

Denifanstat for the treatment of metabolic dysfunction-associated steatohepatitis: a multicentre, double-blind, randomised, placebo-controlled, phase 2b trial [PDF]

Rohit Loomba, Pierre Bédossa, Katharine Grimmer, George Kemble, Eduardo B. Martins, William McCulloch, Marie O’Farrell, Wen-Wei Tsai, Jose Cobiella, Eric Lawitz, Madhavi Rudraraju, Stephen A. Harrison   +11 more
openalex   +1 more source

Sex-specific effects of peptidyl arginine deiminase 4 deficiency in the cafeteria diet-induced obesity-associated metabolic complications

Frontiers in Endocrinology
BackgroundObesity is a global health challenge linked to chronic non-communicable diseases. Low-grade inflammation and altered immune responses, including neutrophil extracellular trap (NET) formation, contribute to metabolic complications.
Andrej Feješ, Emil Bečka, Ivana Feješ Slivková, Kristína Macáková, Emőke Šteňová, Michal Pastorek, Peter Celec, Roman Gardlík, Katarína Šebeková, Veronika Borbélyová   +9 more
doaj   +1 more source

Roles of Traditional and Next-Generation Probiotics on Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH): A Systematic Review and Network Meta-Analysis [PDF]

Yuezhi Zhu, Jen Kit Tan, Jia Liu, Jo Aan Goon   +3 more
openalex   +1 more source