Results 181 to 190 of about 236,526 (353)
Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians
Developmental Dynamics, EarlyView.Abstract Background
CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.Yoichi Saito, Yukio Fujiwara, Yasuka L. Yamaguchi, Satomi S. Tanaka, Kyoko Miura, Yoshiyuki Hizukuri, Kyoko Yamashiro, Yasuhiro Hayashi, Yuta Nakashima, Yoshihiro Komohara +9 morewiley +1 more sourceA nationwide assessment of hepatocellular adenoma resection: Indications and pathological discordance
Hepatology Communications, EarlyView., 2022 Abstract
Hepatocellular adenomas (HCAs) are benign liver tumors associated with bleeding or malignant transformation. Data on the indication for surgery are scarce. We analyzed indications and outcome of patients operated for HCAs < 50 mm compared to HCAs ≥ 50 mm. Changes in final postoperative diagnosis were assessed.Martijn P. D. Haring, Arthur K. E. Elfrink, Christiaan A. J. Oudmaijer, Paul C. M. Andel, Alicia Furumaya, Nenke de Jong, Colin J. J. M. Willems, Thijs Huits, Julie M. L. Sijmons, Eric J. T. Belt, Koop Bosscha, Esther C. J. Consten, Mariëlle M. E. Coolsen, Peter van Duijvendijk, Joris I. Erdmann, Paul Gobardhan, Robbert J. de Haas, Tjarda van Heek, Hwai‐Ding Lam, Wouter K. G. Leclercq, Mike S. L. Liem, Hendrik A. Marsman, Gijs A. Patijn, Türkan Terkivatan, Babs M. Zonderhuis, Izaak Quintus Molenaar, Wouter W. te Riele, Jeroen Hagendoorn, Alexander F. M. Schaapherder, Jan N. M. IJzermans, Carlijn I. Buis, Joost M. Klaase, Koert P. de Jong, Vincent E. de Meijer, the Dutch Benign Liver Tumor Group, R. B. Takkenberg, J. Verheij, O. M. van Delden, J. I. Erdmann, B. V. van Rosmalen, A. Furumaya, G. Kazemier, D. Ramsoekh, J. N. M. IJzermans, R. A. de Man, M. D. Doukas, M. G. Thomeer, A. J. Klompenhouwer, A. F. M. Schaapherder, M. E. Tushuizen, M. J. Coenraad, A. S. L. P. Crobach, M. C. Burgmans, S. Feshtali, M. M. E. Coolsen, M. Kramer, J. C. Beckervordersandforth, I. V. Samarska, C. van der Leij, R. Miclea, J. H. W. de Wilt, P. B. van den Boezem, E. T. T. L. Tjwa, I. Munsterman, S. Vos, S. van Koeverden, V. E. de Meijer, F. J. C. Cuperus, R. J. de Haas, E. W. Duiker, M. P. D. Haring +70 morewiley +1 more sourceExposure to PFAS chemicals induces sex-dependent alterations in key rate-limiting steps of lipid metabolism in liver steatosis
Frontiers in ToxicologyToxicants with the potential to bioaccumulate in humans and animals have long been a cause for concern, particularly due to their association with multiple diseases and organ injuries.Archana Hari, Archana Hari, Mohamed Diwan M. AbdulHameed, Mohamed Diwan M. AbdulHameed, Michele R. Balik-Meisner, Deepak Mav, Dhiral P. Phadke, Elizabeth H. Scholl, Ruchir R. Shah, Warren Casey, Scott S. Auerbach, Anders Wallqvist, Venkat R. Pannala, Venkat R. Pannala +13 moredoaj +1 more sourceLean ZSF1 rats in basic research on heart failure with preserved ejection fraction
ESC Heart Failure, Volume 12, Issue 2, Page 1474-1478, April 2025.Abstract Aims
ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.Petra Büttner, Antje Augstein, Mahmoud Abdellatif, André Lourenço, Adelino Leite‐Moreira, Inês Falcão‐Pires, Sarah Werner, Holger Thiele, Simon Sedej, Antje Schauer, Volker Adams +10 morewiley +1 more sourceSerum levels of caspase-cleaved cytokeratin 18 (CK18-Asp396) predict severity of liver disease in chronic hepatitis B
Clinical and Experimental Gastroenterology, 2017 Juan Li, Auke P Verhaar, Qiuwei Pan, Robert Jacobus de Knegt, Maikel P Peppelenbosch Erasmus MC Cancer Institute, Erasmus MC - University Medical Center Rotterdam, Rotterdam, the Netherlands Background and aim: Caspase-cleaved ...Li J, Verhaar AP, Pan Q, de Knegt RJ, Peppelenbosch MP +4 moredoaj Eicosapentaenoic acid improves hepatic steatosis independent of PPARα activation through inhibition of SREBP-1 maturation in mice
, 2010 Naoki Tanaka, Xiu-Guo Zhang, Eiko Sugiyama, Hiroyuki Kono, Akira Horiuchi, Takero Nakajima, Hiroki Kanbe, Eiji Tanaka, Frank J. Gonzalez, Toshifumi Aoyama +9 moreopenalex +2 more sourcesSemaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity
ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger +12 morewiley +1 more sourceAutomated measurement of liver attenuation to identify moderate-to-severe hepatic steatosis from chest CT scans
, 2019 Artit Jirapatnakul, Anthony P. Reeves, Sara Lewis, Xiangmeng Chen, Teng Ma, Rowena Yip, Xing Chin, Shuang Liu, Ponni Perumalswami, David F. Yankelevitz, Michael Crane, Andrea D. Branch, Claudia I. Henschke +12 moreopenalex +2 more sources
