Magnetic Resonance Imaging Systematically Differs from Histology in Quantifying Macrovesicular Liver Steatosis in Individuals with Morbid Obesity: A Prospective Paired MRI-Histology Study in Bariatric Surgery. [PDF]
Carandina S +3 more
europepmc +1 more source
Immunological and periodontal benefits of prebiotic polydextrose in rats with induced periodontitis
Abstract Background Prebiotic therapy is a promising approach for managing periodontitis due to its potential benefits in modulating the microbiome and the immune response. This study aimed to evaluate the effects of the prebiotic (PREB) polydextrose (PDX) on the development of experimental periodontitis (EP) in rats.
Raquel de S. F Nassar +9 more
wiley +1 more source
ATR-FTIR Assessment of the Antioxidant and Anti-Inflammatory Effects of (-)-Epicatechin in MASLD. [PDF]
Hefer M +6 more
europepmc +1 more source
Abstract Objectives Functional constipation (FC) is common in children with comorbid neurodevelopmental disorders (NDD) and its optimal treatment may be challenged by adherence and medication tolerability issues in this population. We assessed the efficacy and safety of linaclotide in pediatric patients with FC and NDD.
Hannibal Person +9 more
wiley +1 more source
Establishment and Comparative Analysis of Four Mouse Models for the Study of Pancreatic Steatosis. [PDF]
Yin X +5 more
europepmc +1 more source
The utility of whole exome sequencing in diagnosing Wilson disease: A case report
Abstract Wilson disease (WD) is an autosomal recessive disorder of copper metabolism caused by mutations in the ATP7B gene, resulting in toxic copper accumulation in the body. Diagnosis is typically based on biochemistries, including low serum ceruloplasmin and elevated 24‐h urine copper excretion, with Kayser–Fleischer (KF) rings being a supportive ...
Mihir J. Palan +4 more
wiley +1 more source
Machine Learning-Based Radiopatho-Clinical Model Integrating Ultrasound Radiomics and Kleiner Score for Prognosis Prediction in NAFLD-Related Hepatocellular Carcinoma. [PDF]
Li CL +9 more
europepmc +1 more source
Abstract Objectives The efficacy of cystic fibrosis transmembrane conductance regulator (CFTR)‐modulator therapies in preventing or ameliorating cystic fibrosis liver disease (CFLD) by correcting CFTR in cholangiocytes is not well‐documented. This study aimed to assess liver function during CFTR‐modulators.
Laura Giugliano +12 more
wiley +1 more source
Associations of Hand-Grip Strength and Arm Muscle Mass Index Relative to Body Weight with Risk of Non-Alcoholic Fatty Liver Disease in Wheelchair Users. [PDF]
Kim M, Kim J, Lee I.
europepmc +1 more source
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen +11 more
wiley +1 more source

