Results 181 to 190 of about 116,875 (269)

Associations of TyG-related indices with NAFLD-related outcomes: A systematic review and meta-analysis. [PDF]

Medicine (Baltimore)
Li J, Liu W.
europepmc   +1 more source

Melatonin Promotes Improvement in Serum Lipid Levels and Liver Histopathology in Hyperlipidemic Rats

Lipids, EarlyView.
ABSTRACT Hyperlipidemia or dyslipidemia is the term used for the increase in lipid levels in blood plasma, usually occurring due to a high‐fat diet associated with a sedentary lifestyle. The increase in lipid levels can cause fatty infiltration in the liver known as hepatic steatosis, which can lead to inflammation, fibrosis, and necrosis consecutively.
Ana Cláudia Carvalho de Sousa, Jaiurte Gomes Martins da Silva, Érique Ricardo Alves, Laís Caroline da Silva Santos, Bruno José do Nascimento, Marcelle Mariana Sales de França, Vanessa Bischoff Medina, Ismaela Maria Ferreira de Melo, Álvaro Aguiar Coelho Teixeira, Valéria Wanderley Teixeira   +9 more
wiley   +1 more source

Predicting MASLD in People With HIV Using Anthropometric Measures: A Multicenter Cross-Sectional Study. [PDF]

Open Forum Infect Dis
Slim J, Qirem M, Bellafiore P, Tewoldemedhin B, Shahin TB, Leyden K, Poblete R, Nagarakanti S, Vargas H.   +8 more
europepmc   +1 more source

Antimicrobial Photodynamic Therapy Associated With Systemic Treatment in Osteoradionecrosis: An In Vivo Study

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objective To evaluate the effects of antimicrobial photodynamic therapy (aPDT), systemic pharmacological therapy, and their combination on irradiated mandibular post‐extraction bone repair relevant to osteoradionecrosis (ORN) development in a rat model. Methods Twenty‐six male Wistar rats were initially randomized into five experimental groups:
Larissa Lopes Fonseca, Lorena dos Reis Pereira Queiroz, Andréia Luiza Oliveira Costa, Cristina Paixão Durães, Renata Sousa Leite, Ludmila Martins Delazeri, Sérgio Henrique Sousa Santos, Alfredo Maurício Batista de Paula, Lucyana Conceição Farias, André Luiz Sena Guimarães   +9 more
wiley   +1 more source

Discordance Between Conventional Ultrasound and Transient Elastography in Hepatic Steatosis Assessment: Clinical Factors Associated with Discrepant Findings. [PDF]

Diagnostics (Basel)
Brisc MC, Babeș EE, Călugăr-Șolea SF, Bota S, Maghiar L, Brisc CM, Brisc C.   +6 more
europepmc   +1 more source

Advances in quantitative ultrasound for metabolic dysfunction-associated steatotic liver disease diagnosis. [PDF]

Front Physiol
Ma Z, Liu B, Zhou S, Yang S, Sun X, Jiang X, Sun X.   +6 more
europepmc   +1 more source

Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications

Med Research, EarlyView.
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang, Fen Yang, Xingji Lian, Jie He, Shuijin Huang, Mingjuan Fan, Yin Liang, Jiaqiang Huang, LongYan Yin, Hong Wang   +9 more
wiley   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Stage-dependent dynamics of Apolipoprotein C3 across the spectrum of MASLD. [PDF]

PLoS One
Messer EK, Fischer J, Herta T, Boehlig A, Matz-Soja M, Tuennemann-Tarr A, Gaul S, Laufs U, Berg T.   +8 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source