Hepatocyte Models for Metabolic Dysfunction-Associated Steatotic Liver Disease: A Comparative Analysis of Non-HepG2 Cell Models. [PDF]
Kotlyarova A, Kotlyarov S.
europepmc +1 more source
Intelligent design of artificial biocatalyst for biomedical diseases
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang +3 more
wiley +1 more source
The Degree of Liver Steatosis Is Associated with Abnormally High Serum Levels of Markers of Blood-Brain Barrier Dysfunction and Systemic Inflammation in Patients with Morbid Obesity. [PDF]
Hurtado-Alvarado G +11 more
europepmc +1 more source
ABSTRACT Background The impact of deep learning (DL) reconstruction and segmentation on MRI radiomics stability has not been fully assessed. Purpose To investigate the effects of acquisition, reconstruction, and segmentation on the reproducibility and variability of radiomic features in abdominal MRI. Study Type Prospective.
Jingyu Zhong +14 more
wiley +1 more source
Accurate and spatially stable quantification of hepatic steatosis using ultrasound-derived fat fraction in metabolic dysfunction-associated steatotic liver disease (MASLD): a prospective magnetic resonance imaging-proton density fat fraction (MRI-PDFF) study. [PDF]
Wang SR +5 more
europepmc +1 more source
ABSTRACT Background In chronic liver disease, fat and fibroinflammatory changes often coexist. However, their biomarkers, proton density fat fraction (PDFF) and T1, are typically assessed separately. Their reproducibility under mutual confounding remains unclear.
Jitka Starekova +13 more
wiley +1 more source
Prevalence and Association of Liver Steatosis and Non-Alcoholic Pancreatic Steatosis in Very High Cardiovascular Risk. [PDF]
Gómez-Mendoza R +7 more
europepmc +1 more source
ABSTRACT Background Antiretroviral therapy has transformed HIV into a chronic condition, yet cardiac injury remains a major issue. Purpose To assess the ability of cardiac MR imaging markers to predict cardiac injury and disease progression in HIV‐infected individuals. Study Type Prospective.
Chunyan Deng +5 more
wiley +1 more source

