Results 171 to 180 of about 5,456,142 (288)

Metabolic Dysfunction-Associated Steatotic Liver Disease and Risk of Depressive Symptoms in Older Adults. [PDF]

Int J Geriatr Psychiatry
Nasr Azadani M, Davoodian N, Berk M, Clayton-Chubb D, Forbes M, Ganjali S, Kemp W, Woods RL, Lotfaliany M, McNeil JJ, Pasco JA, Roberts SK, Mohebbi M.   +12 more
europepmc   +1 more source

Review Article: Fibrosis Reversal in Metabolic Dysfunction‐Associated Steatohepatitis—The Promise of Emerging Therapeutics

Alimentary Pharmacology &Therapeutics, EarlyView.
Metabolic dysfunction‐associated steatohepatitis is the second commonest US indication for liver transplantation but remains largely undiagnosed and untreated. Fibrosis stage is the strongest predictor of major adverse liver outcomes, with decompensation rates and transplant‐free survival diverging sharply between F3 and F4, while cardiovascular ...
Malek Ayoub, Tsubasa Tsutsumi, Mary E. Rinella   +2 more
wiley   +1 more source

Extracellular Vesicle Surface Protein Profiling in Metabolic Dysfunction-associated Steatotic Liver Disease in Obesity. [PDF]

J Extracell Biol
Garcia NA, Kløve-Mogensen K, Cliff KL, Bæk R, Ulanowska M, Quezada JAD, Jørgensen MM, Handberg A, Mellergaard M.   +8 more
europepmc   +1 more source

Re‐thinking peripheral dysfunctions in obesity: The emerging role of sulphaceutics and sulphanutraceutics

British Journal of Pharmacology, EarlyView.
Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo, Veronica Casale, Roberta d'Emmanuele di Villa Bianca, Valentina Vellecco, Mariarosaria Bucci   +4 more
wiley   +1 more source

Hepatic Lipoprotein Production, Cardiometabolic Phenotypes, and Subtypes of Steatotic Liver Disease. [PDF]

Circ Res
Davidson NO.
europepmc   +1 more source

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

British Journal of Pharmacology, EarlyView.
Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra, Francesco Niro, Marco Mergiotti, Giovanni Gavatorta, Emilio Hirsch, Alessandra Ghigo   +5 more
wiley   +1 more source

Metabolic Dysfunction-Associated Steatotic Liver Disease in Adults With Acromegaly: A Meta-Analysis of Observational Studies. [PDF]

Diabetes Metab Res Rev
Mantovani A, Morandin R, Molinaroli E, Messetti D, Rolli N, Forti M, Zoco M, Polyzos SA, Targher G.   +8 more
europepmc   +1 more source

Psychological Stress Promotes Tumor Growth in Hepatocellular Carcinoma Models Through Myeloid Signaling

Cancer Science, EarlyView.
Psychological stress promotes hepatocellular carcinoma progression through coordinated regulation of macrophages and neutrophils. Noradrenaline activates ADRB2 signaling in intratumoral macrophages, leading to CXCL2 production and neutrophil recruitment.
Keita Ogawa, Takahiro Aoki, Tatsuya Kaneko, Hongxuan Wang, Daiki Shimizu, Daisuke Katsumi, Iori Kojima, Hidekazu Tanaka, Kiwamu Motoyoshi, Ko Ozaki, Katsuhiro Nishimura, Tomohisa Iinuma, Mariko Takami, Shinichiro Motohashi   +13 more
wiley   +1 more source

Steatosis in Cirrhosis: A Prognostic Marker for Liver-Related Outcomes in Metabolic-Dysfunction Associated Steatotic Liver Disease. [PDF]

Liver Int
Pei Y, Ren Y, Tai D, Yuan HY, Su RY, Zulqarnain M, Puspanathan P, Mahadeva S, Leow WQ, Lim T, Tan CK, Chang PJ, Zheng MH, Chan WK, Goh GBB.   +14 more
europepmc   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

Cell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang, Xiaotian Qu, Jinhong Si, Junkang Meng, Ting Zhang, Shuliang Niu   +5 more
wiley   +1 more source