Results 211 to 220 of about 22,335 (252)
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Lipid droplets in steatotic liver disease

Current Opinion in Clinical Nutrition & Metabolic Care, 2023
Purpose of review This review aims to discuss the most recent evidence exploring the role of lipid droplets in steatotic liver disease (SLD). We highlight the breadth of mechanisms by which lipid droplets may contribute to the progression of SLD with a particular focus on the role of lipid droplets as inducers of mechanical ...
Josh, Bilson, Eleonora, Scorletti
openaire   +2 more sources

Screening for advanced steatotic liver disease

The Lancet Gastroenterology & Hepatology
Steatotic liver disease often progresses asymptomatically, with the risk of advancing to cirrhosis and liver cancer. Early detection of advanced liver disease through screening presents an opportunity to prevent severe outcomes, if said screening is linked to effective intervention.
Johansen, Stine; id_orcid 0000-0002-5031-2294   +3 more
openaire   +4 more sources

Chronic Hepatitis C Related Steatotic Liver Disease Is More Than “Miscellaneous Steatotic Liver Disease”

Clinical Gastroenterology and Hepatology
The terminology and definition of fatty liver disease has evolved significantly. Recently, the overarching term of steatotic liver disease (SLD) has been endorsed by international societies.1,2 SLD further encompasses individuals with cardiometabolic risk factors (CMRFs), namely, metabolic dysfunction-associated steatotic liver disease (MASLD).
Ming-Lung Yu   +2 more
exaly   +3 more sources

Role of steatotic liver disease in prediction and prevention of cardiometabolic diseases

Nature Reviews Gastroenterology & Hepatology, 2023
Steatotic liver disease has emerged as an important risk factor for cardiovascular disease, type 2 diabetes mellitus and chronic kidney disease. Successful treatment of steatotic liver disease might also be effective in preventing these cardiometabolic diseases.
Norbert Stefan   +2 more
openaire   +3 more sources

Steatotic liver disease after pediatric liver transplantation

Liver Transplantation
Metabolic dysfunction–associated steatotic liver disease is becoming an increasingly frequent cause of chronic liver disease in children. It has been reported as a complication of liver transplantation in adults but remains poorly evaluated in liver-transplanted children.
Wischlen, Emma   +9 more
openaire   +2 more sources

Role of Neutrophils in the Development of Steatotic Liver Disease

Seminars in Liver Disease
This review explores the biological aspects of neutrophils, their contributions to the development of steatotic liver disease, and their potential as therapeutic targets for the disease. Although alcohol-associated and metabolic dysfunction-associated liver diseases originate from distinct etiological factors, the two diseases frequently share ...
You-Jin, Choi   +2 more
openaire   +2 more sources

Steatotic Liver Disease: Pathophysiology and Emerging Pharmacotherapies

Pharmacological Reviews
Steatotic liver disease (SLD) displays a dynamic and complex disease phenotype. Consequently, the metabolic dysfunction-associated steatotic liver disease (MASLD)/metabolic dysfunction-associated steatohepatitis (MASH) therapeutic pipeline is expanding rapidly and in multiple directions.
Michail Kokkorakis   +6 more
openaire   +2 more sources

Editorial: Crystalising the burden of steatotic liver disease

Alimentary Pharmacology & Therapeutics
LINKED CONTENTThis article is linked to Schneider et al papers.
Luis Calzadilla Bertot, Leon A. Adams
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Steatotic Liver Diseases (SLDs): A Review

Journal of Insurance Medicine
Liver steatosis is now the politically correct term for excessive fat in the liver (fatty liver). Its incidence and prevalence, in lockstep with diabetes and obesity, continue to climb to over 2 billion persons worldwide. It is the most common cause of chronic liver disease and the leading cause of liver-related morbidity and mortality. This treatise,
openaire   +2 more sources

Steatotic liver disease and HIV: an agenda for 2030

The Lancet HIV
People living with HIV are particularly susceptible to developing metabolic disorders, including metabolic dysfunction-associated steatotic liver disease and other forms of SLD. However, people living with HIV have been historically excluded from clinical trials and large cohort studies of SLD.
Pericàs, Juan M   +12 more
openaire   +2 more sources

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