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Steatotic liver disease, MASLD and risk of chronic kidney disease
Diabetes and MetabolismWith the rising tide of fatty liver disease related to metabolic dysfunction worldwide, the association of this common liver disease with chronic kidney disease (CKD) has become increasingly evident. In 2020, the more inclusive term metabolic dysfunction-associated fatty liver disease (MAFLD) was proposed to replace the old term non-alcoholic fatty ...
Christopher D Byrne +2 more
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Liver and atherosclerotic risks of patients with cryptogenic steatotic liver disease
Hepatology InternationalIn 2023, a new nomenclature of "metabolic associated steatotic liver disease" (MASLD) has emerged by incorporating cardio-metabolic criteria to redefine "non-alcoholic fatty liver disease" (NAFLD). Among steatotic liver disease (SLD), those having no known causes and without any one of cardio-metabolic criteria are deemed to have cryptogenic SLD.
Shao-Wen Wang +4 more
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Detecting at-risk steatotic liver disease and liver fibrosis in the community
HepatologyAdvanced liver fibrosis and “At-Risk” metabolic dysfunction-associated steatohepatitis (At-Risk MASH) are present in 5% and 10%, respectively, of community-based patients with steatotic liver disease and metabolic risk factors and/or excess alcohol consumption.
Leon A. Adams +2 more
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Precision medicine in steatotic liver disease
Current Opinion in GastroenterologyPurpose of review Discuss advances in genomics, metabolomics, and proteomics in steatotic liver disease. Recent findings Common genetic variants in genes including PNPLA3
Vitchapong Prasitsumrit, Vincent L. Chen
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Lipid droplets in steatotic liver disease [PDF]
Purpose of review: this review aims to discuss the most recent evidence exploring the role of lipid droplets in steatotic liver disease (SLD). We highlight the breadth of mechanisms by which lipid droplets may contribute to the progression of SLD with a particular focus on the role of lipid droplets as inducers of mechanical stress within hepatocytes ...
Bilson, Josh, Scorletti, Eleonora
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Exploring the landscape of steatotic liver disease in the general US population
Liver International, 2023Pietro Invernizzi
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Mechanisms of liver regeneration and their relevance to steatotic liver disease
American Journal of Physiology-Gastrointestinal and Liver PhysiologyGary Huang, V. Nathan Subramaniam
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