Results 81 to 90 of about 201,880 (241)

The Conditions of Primary Infection Define the Load of Latent Viral Genome in Organs and the Risk of Recurrent Cytomegalovirus Disease [PDF]

, 1994
Recurrence of cytomegalovirus (CMV) from latency is a frequent cause of disease in immunocompromised patients. To date, there is no explanation for the diversity in the clinical manifestations.
Balthesen, Monika, Jonjic, Stipan, Koszinowski, Ulrich H., Pavic, Ivica, Rapp, Maria, Reddehase, Matthias J.   +5 more
core   +4 more sources

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

Universell utforming og den vanskelige avgrensingen av «alle»

FORMakademisk, 2013
Universell utforming er et prinsipp hvor målsetningen er at «utforming av produkter og omgivelser [skal skje] på en slik måte at de kan brukes av alle mennesker, i så stor utstrekning som mulig, uten behov for tilpassing og en spesiell utforming ...
Lars Christian Risan, Siri Nørve
doaj   +1 more source

Quantum yield optimized fluorophores for site-specific labeling and super-resolution imaging

, 2011
Single molecule applications, saturated pattern excitation microscopy, or stimulated emission depletion (STED) microscopy demand for bright and highly stable fluorescent dyes1,2.
Choquet, Daniel, Cognet, Laurent, Giannone, Gregory, Grunwald, Christian, Lounis, Brahim, Schulze, Katrin, Tampé, Robert   +6 more
core   +3 more sources

Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia. [PDF]

, 2019
Cultured mouse peritoneal macrophages release large numbers of ~30-nm cholesterol-rich particles. Here, we show that those particles represent fragments of the plasma membrane that are pulled away and left behind during the projection and retraction of ...
Fong, Loren G, He, Cuiwen, Heizer, Patrick J, Hu, Xuchen, Jiang, Haibo, Jung, Rachel S, Tontonoz, Peter, Tu, Yiping, Weston, Thomas A, Wohlschlegel, James A, Young, Brian D, Young, Stephen G   +11 more
core   +3 more sources

miR‐9 Restricts Insulin Secretion by Targeting Rab34, Which Mediates Lysosomal Degradation of Proinsulin

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Insulin secretion is a complex, vesicular transport process. Rab34 is a key regulator of intracellular vesicle transport; however, its role in insulin secretion has not yet been reported. miRNA‐9 is vital for the development and progression of the diagnosis and treatment of type 2 diabetes. This study aimed to investigate whether miR‐9 targets
Zhen‐Zhen Guo, Ao‐Ying Li, Ting‐Ting Xiang, Zu‐Hao Zhang, Ao Deng, Yang Han   +5 more
wiley   +1 more source

Fluorochrome separation by fluorescence lifetime phasor analysis in confocal and STED microscopy

Methods in Microscopy
In fluorescence microscopy, discrimination of fluorochromes in multi-color labeling was originally based on the emission spectrum only, then on emission and distinct excitation wavelengths.
Gonzalez Pisfil Mariano, Dietzel Steffen
doaj   +1 more source

Cellular delivery of antibodies: effective targeted subcellular imaging and new therapeutic tool [PDF]

, 2010
It is already more than a century since the pioneering work of the Nobel Laureate Ehrlich gave birth to the side chain theory1, which helped to define antibodies and their ability to target specific biological sites.
Andrew L. Lewis, Giuseppe Battaglia, Irene Canton, Marzia Massignani, Nicholas J. Warren, Nisa Patikarnmonthon, Steven P. Armes   +6 more
core   +1 more source

Multiphoton Label-Free ex-vivo imaging using a custom-built dual-wavelength microscope with chromatic aberrations compensation

, 2017
Label-Free Multiphoton Microscopy is a very powerful optical microscopy that can be applied to study samples with no need for exogenous fluorescent probes, keeping the main benefits of a Multiphoton approach, like longer penetration depths and intrinsic ...
Armani, Andrea, Borile, Giulia, Filippi, Andrea, Gerosa, Gino, Gintoli, Michele, Iop, Laura, Romanato, Filippo, Sandri, Marco, Sasso, Eleonora Dal   +8 more
core   +1 more source

Foundations of Sted Microscopy

, 2014
This chapter presents the foundations of STED microscopy with a comparison to its generalization Resolft microscopy and to stochastic imaging methods (PALM, STORM, FPALM, and alike). The first section reviews the advantages of optical microscopy, explains the diffraction limit, and shows how the classical resolution limit was finally broken.
Lauterbach, M, Eggeling, C
openaire   +1 more source