Results 121 to 130 of about 5,920,212 (288)
We measured lithium (Li) abundance and instantaneous chromospheric Ca ii HK activity in Hamilton Echelle Spectrograph observations of 211 solar analog field stars, with one objective being potential identification of grand minimum candidates for ongoing ...
Dan Lubin +4 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Molecular Hydrogen Controls the Temperatures of Flares on TRAPPIST-1
Early JWST observations of TRAPPIST-1 have revealed an unexpected puzzle: energetic white-light flares ( E > 10 ^30 erg) reach temperatures of only ∼3500–4000 K, nearly 3 times cooler than typical solar flares, which peak around 9000–10,000 K.
A. I. Shapiro +9 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
This is a non-exhaustive review of what we have learned from 10+ years of cluster studies with multi-object spectrographs at 10 m-class telescopes about what stars do with their birth-cloud lithium.
A.J. Korn, Korn, Andreas,
core +1 more source
Antisolar Differential Rotation May Have Revived Magnetic Braking in the Subgiant 31 Aquilae
Recent observations have shown that sufficiently slow rotation disrupts the organization of large-scale magnetic field in older main-sequence stars, leading to weakened magnetic braking (WMB) and a collapse in the efficiency of the global stellar dynamo.
Travis S. Metcalfe +18 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Activity theory: A framework for analysing intercultural academic activity [PDF]
This article suggests that Activity Theory (AT) can be applied as a holistic framework to analyse the complex sociocultural issues that arise when academics wish to engage in collaborative activity across institutional and cultural boundaries.
Barnard, Roger, 2245
core

