Results 141 to 150 of about 15,327 (291)
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Stellar Models Also Limit Exoplanet Atmosphere Studies in Emission
International audienceStellar contamination has long been recognized as a major bottleneck in transmission spectroscopy, limiting our ability to accurately characterize exoplanet atmospheres—particularly for terrestrial worlds.
de Wit, Julien +5 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Far-ultraviolet Emission Line Investigation of Flares on AU Mic
The role of nonthermal proton energy transportation during solar and stellar flares is largely unknown; a better understanding of this physical process will allow us to rectify longstanding deficiencies in flare models.
Adalyn Gibson +2 more
doaj +1 more source
An apodized Kepler periodogram for separating planetary and stellar activity signals. [PDF]
Gregory PC.
europepmc +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The He I D3 Line as a Proxy for Magnetic Activity Using EXPRES Solar Observations
Stellar activity remains one of the primary challenges in the detection and characterization of low-mass exoplanets, as it can induce radial velocity (RV) variations that mask or mimic planetary signals. Identifying reliable activity proxies is essential
Momo Ellwarth +8 more
doaj +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Predicting Photospheric Ultraviolet Emission from Stellar Evolutionary Models
Stellar ultraviolet (UV) emission serves as a crucial indicator for estimating magnetic activity and evaluating the habitability of exoplanets orbiting stars.
Song Wang +3 more
doaj +1 more source

