Results 141 to 150 of about 15,327 (291)

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Stellar Models Also Limit Exoplanet Atmosphere Studies in Emission

open access: yes
International audienceStellar contamination has long been recognized as a major bottleneck in transmission spectroscopy, limiting our ability to accurately characterize exoplanet atmospheres—particularly for terrestrial worlds.
de Wit, Julien   +5 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Far-ultraviolet Emission Line Investigation of Flares on AU Mic

open access: yesThe Astrophysical Journal
The role of nonthermal proton energy transportation during solar and stellar flares is largely unknown; a better understanding of this physical process will allow us to rectify longstanding deficiencies in flare models.
Adalyn Gibson   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The He I D3 Line as a Proxy for Magnetic Activity Using EXPRES Solar Observations

open access: yesThe Astrophysical Journal
Stellar activity remains one of the primary challenges in the detection and characterization of low-mass exoplanets, as it can induce radial velocity (RV) variations that mask or mimic planetary signals. Identifying reliable activity proxies is essential
Momo Ellwarth   +8 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Predicting Photospheric Ultraviolet Emission from Stellar Evolutionary Models

open access: yesThe Astrophysical Journal
Stellar ultraviolet (UV) emission serves as a crucial indicator for estimating magnetic activity and evaluating the habitability of exoplanets orbiting stars.
Song Wang   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy