Results 111 to 120 of about 40,509 (299)

Stellar population in star formation regions of galaxies

Open Astronomy, 2018
We developed techniques for searching young unresolved star groupings (clusters, associations, and their complexes) and of estimating their physical parameters.
Gusev Alexander S., Shimanovskaya Elena V., Shatsky Nikolai I., Sakhibov Firouz, Piskunov Anatoly E., Kharchenko Nina V.   +5 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Evidence of the Galactic outer ring R1R2' from young open clusters and OB-associations

, 2016
The distribution of young open clusters in the Galactic plane within 3 kpc from the Sun suggests the existence of the outer ring R1R2' in the Galaxy.
Dambis, A. K., Glushkova, E. V., Melnik, A. M., Rautiainen, P.   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The VLT-FLAMES survey of massive stars: Wind properties and evolution of hot massive stars in the LMC

, 2007
[Abridged] We have studied the optical spectra of 28 O- and early B-type stars in the Large Magellanic Cloud, 22 of which are associated with the young star-forming region N11.
Afd Astrophysics begr 1/1/17, Astrophysics, Crowther, P.A., de Koter, A., Evans, C.J., Herrero, A., Langer, N., Lennon, D.J., Mokiem, M.R., Najarro, F., Puls, J., Smartt, S.J., Villamariz, M.R., Vink, J.S.   +13 more
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

PAH Feature Ratios around Stellar Clusters and Associations in 19 Nearby Galaxies

The Astronomical Journal
We present a comparison of observed polycyclic aromatic hydrocarbon (PAH) feature ratios in 19 nearby galaxies with a grid of theoretical expectations for near- and mid-infrared dust emission.
Daniel A. Dale, Gabrielle B. Graham, Ashley T. Barnes, Dalya Baron, Frank Bigiel, Médéric Boquien, Rupali Chandar, Jérémy Chastenet, Ryan Chown, Oleg V. Egorov, Simon C. O. Glover, Lindsey Hands, Kiana F. Henny, Remy Indebetouw, Ralf S. Klessen, Kirsten L. Larson, Janice C. Lee, Adam K. Leroy, Daniel Maschmann, Debosmita Pathak, M. Jimena Rodríguez, Erik Rosolowsky, Karin Sandstrom, Eva Schinnerer, Jessica Sutter, David A. Thilker, Tony D. Weinbeck, Bradley C. Whitmore, Thomas G. Williams, Aida Wofford   +29 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source