Results 121 to 130 of about 40,509 (299)
The Age Distribution of Stellar Orbit Space Clumps
The orbit distribution of young stars in the Galactic disk is highly structured, from well-defined clusters to streams of stars that may be widely dispersed across the sky, but are compact in orbital action-angle space.
Verena Fürnkranz +3 more
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The Mass of the Vela Pulsar Progenitor and the Age of the Vela-Puppis Complex
The association of the Vela Pulsar with the Vela Supernova Remnant has long supported the hypothesis that core-collapse supernovae yield neutron stars, but its surrounding stellar population now offers new insights into progenitor evolution.
Jeremiah W. Murphy +6 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
ChronoFlow: A Data-driven Model for Gyrochronology
Gyrochronology is a technique for constraining stellar ages using rotation periods, which change over a star’s main-sequence (MS) lifetime due to magnetic braking. This technique shows promise for MS FGKM stars, where other methods are imprecise. However,
Phil R. Van-Lane +7 more
doaj +1 more source
The Orion OB1 Association I. Stellar content
Walraven photometry of established and probable members of the Orion OB1 association is presented. Effective temperature, surface gravity, luminosity and mass are derived for all stars, using atmosphere models by Kurucz (1979). Absolute magnitudes are calculated using the Straizys and Kuriliene (1981) tables.
Brown, A. G. A. +2 more
openaire +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
The Herbig–Haro Outflow Content and Star-forming Environment of Circinus West and East
We report the results of a spatially compete, high-sensitivity survey for Herbig–Haro (HH) outflows in the Western and Eastern Circinus molecular clouds.
T. A. Rector +4 more
doaj +1 more source

