Results 141 to 150 of about 41,072 (339)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The stellar initial mass function of nearby young moving groups

Astronomy & Astrophysics
Context. The solar neighbourhood is populated by nearby (
Bertolotto-Stefanelli Rafael, José Downes Juan, Suárez Genaro, Mateu Cecilia, Gagné Jonathan, Román Zúñiga Carlos   +5 more
doaj   +1 more source

Possible Association of Two Stellar Bowshocks with Unidentified Fermi Sources [PDF]

, 2018
E. Sánchez-Ayaso, M. V. del Valle, J. Martı́, Gustavo E. Romero, Pedro L. Luque‐Escamilla   +4 more
openalex   +1 more source

A new study on a type Iax stellar remnant and its probable association with SN 1181 [PDF]

, 2022
F. Lykou, Q. A. Parker, Andreas Ritter, A. A. Zijlstra, D. J. Hillier, M. A. Guerrero, Pascal Le Dû   +6 more
openalex   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Age Distribution of Stellar Orbit Space Clumps

The Astrophysical Journal
The orbit distribution of young stars in the Galactic disk is highly structured, from well-defined clusters to streams of stars that may be widely dispersed across the sky, but are compact in orbital action-angle space.
Verena Fürnkranz, Hans-Walter Rix, Johanna Coronado, Rhys Seeburger   +3 more
doaj   +1 more source

Stellar companions and Jupiter-like planets in young associations [PDF]

R. Gratton, M. Bonavita, D. Mesa, S. Desidera, A. Zurlo, Sebastián Marino, V. D’Orazi, E. Rigliaco, V. Nascimbeni, D. Barbato, G. Columba, V. Squicciarini   +11 more
openalex   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Mass of the Vela Pulsar Progenitor and the Age of the Vela-Puppis Complex

The Astrophysical Journal
The association of the Vela Pulsar with the Vela Supernova Remnant has long supported the hypothesis that core-collapse supernovae yield neutron stars, but its surrounding stellar population now offers new insights into progenitor evolution.
Jeremiah W. Murphy, Andrés F. Barrientos, René Andrae, Joseph Guzman, Benjamin F. Williams, Julianne J. Dalcanton, Brad Koplitz   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source