Results 51 to 60 of about 4,175 (313)

Characterization of stellar and sub-stellar atmospheres

open access: yes, 2016
In this work I aim characterize a number of (sub)-stellar companions. When studying isolated brown dwarfs, very low-mass stars, and directly imaged exoplanets with insignificant orbital motion, we have to rely on theoretical models to determine basic parameters such as mass, age, and consequently, effective temperature and surface gravity.
openaire   +2 more sources

Dislocations in Magnetohydrodynamic Waves in a Stellar Atmosphere [PDF]

open access: yesPhysical Review Letters, 2013
We describe the presence of wavefront dislocations in magnetohydrodynamic waves in stratified stellar atmospheres. Scalar dislocations such as edges and vortices can appear in Alfv n waves, as well as in general magneto-acoustic waves. We detect those dislocations in observations of magnetohydrodynamic waves in sunspots in the solar chromosphere ...
A. López Ariste   +2 more
openaire   +5 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

First JWST/NIRSpec Spectroscopy of O Stars in the Small Magellanic Cloud

open access: yesThe Astrophysical Journal Letters
Determining how much mass is removed by stellar winds is crucial to understanding massive star evolution and feedback. However, traditional spectroscopic diagnostics in the UV and optical are not sensitive enough to characterize weak stellar winds of OB ...
Armin Mang Román   +12 more
doaj   +1 more source

Modeling the TESS Light Curve of Ap Si Star MX TrA

open access: yesUniverse
The TESS light curve of the silicon Ap star MX TrA was modeled using the observational surface distribution of silicon, iron, helium, and chromium obtained previously with the Doppler Imaging technique.
Yury Pakhomov   +3 more
doaj   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Exploring the Small-scale Magnetic Fields of the Solar Analog KIC 8006161 Using Asteroseismology

open access: yesThe Astrophysical Journal
The magnetic field is a significant and universal physical phenomenon in modern astrophysics. Small-scale magnetic fields are very important in the stellar atmosphere. They are ubiquitous and strongly couple with acoustic waves. Therefore, their presence
Guifang Lin   +4 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

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